Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 8/20 | 0.32 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.32 |
| ▸ | GCK | P35557 | 2/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15528548 | 0.87 | RORC (0.32) | RORCNR1H2NR1H3MTNR1APPARG | |
| SCHEMBL11472931 | 0.69 | AR (0.42) | RORCNR1H2NR1H3NR1I2AR | |
| SCHEMBL7140193 | 0.67 | MTNR1A (0.34) | MTNR1A | |
| SCHEMBL6754202 | 0.67 | AR (0.38) | AR | |
| SCHEMBL6754201 | 0.67 | AR (0.38) | AR | |
| SCHEMBL3625724 | 0.67 | GAA (0.42) | RORCNR1H2NR1H3NR1I2AR | |
| SCHEMBL15525689 | 0.66 | NR1H3 (0.44) | RORCNR1H2NR1H3GCKNR1I2 | |
| SCHEMBL21787545 | 0.65 | RORC (0.55) | RORCNR1H3NR1I2 | |
| SCHEMBL16564739 | 0.65 | RORC (0.39) | RORCMTNR1A | |
| SCHEMBL30738393 | 0.65 | AR (0.52) | MTNR1AAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2844247-A1 | ROR MODULATORS AND THEIR USES | Gaweco, Anderson (US) | 2015-03-11 | — | — | EP | disclosed |
| WO-2013159095-A1 | ROR MODULATORS AND THEIR USES | GAWECO ANDERSON (US) | 2013-10-24 | — | — | WO | disclosed |