Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 20/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16564739 | 0.74 | RORC (0.39) | RORC | |
| SCHEMBL16553844 | 0.72 | RORC (0.49) | RORCNR1H3 | |
| SCHEMBL16564686 | 0.71 | GAA (0.46) | RORCNR1I2NR1H3 | |
| SCHEMBL16564892 | 0.71 | RORC (0.88) | RORCNR1I2NR1H3 | |
| SCHEMBL18197118 | 0.71 | RORC (1.00) | RORCNR1I2NR1H3 | |
| SCHEMBL11472931 | 0.71 | AR (0.42) | RORCNR1I2NR1H3 | |
| SCHEMBL3625724 | 0.67 | GAA (0.42) | RORCNR1I2NR1H3 | |
| SCHEMBL22297828 | 0.66 | AR (0.43) | — | |
| SCHEMBL15528548 | 0.66 | RORC (0.32) | RORCNR1I2NR1H3 | |
| SCHEMBL6752933 | 0.66 | AR (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020047487-A1 | METHODS FOR TREATING CANCER WITH RORGAMMA INHIBITORS AND STATINS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-03-05 | — | — | WO | disclosed |