SCHEMBL1552576

SCHEMBL1552576

Cc1cc2c(cc1C)C(Nc1ncnc(N)n1)CC2

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.44
GAA P10253 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
HTT P42858 1/20 0.39
RAB9A P51151 1/20 0.38
MKNK1 Q9BUB5 5/20 0.34
BCL6 P41182 1/20 0.33
EGFR P00533 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
ADORA3 P0DMS8 1/20 0.32
SLC6A2 P23975 1/20 0.32
PDE4A P27815 1/20 0.32
KDR P35968 1/20 0.32
IDH1 O75874 2/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11960089 1.00 KDM4E (0.44) KDM4EGAAL3MBTL1HTTRAB9A
SCHEMBL1552577 1.00 KDM4E (0.44) KDM4EGAAL3MBTL1HTTRAB9A
SCHEMBL5436950 0.90 KDM4E (0.38) KDM4EGAAL3MBTL1HTTRAB9A
SCHEMBL1552313 0.90 KDM4E (0.38) KDM4EGAAL3MBTL1HTTRAB9A
SCHEMBL1552309 0.90 KDM4E (0.38) KDM4EGAAL3MBTL1HTTRAB9A
SCHEMBL1551697 0.85 RAB9A (0.45) KDM4EGAAL3MBTL1HTTRAB9A
SCHEMBL1551809 0.85 RAB9A (0.45) KDM4EGAAL3MBTL1HTTRAB9A
SCHEMBL1551701 0.85 RAB9A (0.45) KDM4EGAAL3MBTL1HTTRAB9A
SCHEMBL11960147 0.83 DDB1 (0.33) KDM4EGAAL3MBTL1IDH1
SCHEMBL11960088 0.83 DDB1 (0.33) KDM4EGAAL3MBTL1IDH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE47666-E1 Herbicidal compositions BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2019-10-29 US disclosed
US-RE46095-E1 Herbicidal compositions BAYER INTELLECTUAL PROPERTY GMBH (DE) 2016-08-09 US disclosed
US-RE46095-E1 Herbicidal compositions BAYER INTELLECTUAL PROPERTY GMBH (DE) 2016-08-09 US disclosed
US-8586503-B2 Herbicidal compositions BAYER CROPSCIENCE AG (DE) 2013-11-19 US disclosed
US-8426342-B2 Method for weed control in lawn BAYER CROPSCIENCE AG (DE) 2013-04-23 US disclosed
US-8426342-B2 Method for weed control in lawn BAYER CROPSCIENCE AG (DE) 2013-04-23 US disclosed
US-8236729-B2 Synergistic mixtures BAYER CROPSCIENCE AG (DE) 2012-08-07 US disclosed
US-8236729-B2 Synergistic mixtures BAYER CROPSCIENCE AG (DE) 2012-08-07 US disclosed
EP-2012588-B1 AQUEOUS SUSPENSION CONCENTRATE BAYER CROPSCIENCE AG (DE) 2011-04-27 EP disclosed
US-20100048400-A1 HERBICIDE COMBINATION BAYER CROPSCIENCE AG (DE) 2010-02-25 US disclosed
WO-2010009819-A2 METHOD FOR WEED CONTROL IN LAWN BAYER CROPSCIENCE AG (DE) 2010-01-28 WO disclosed
US-20100016158-A1 METHOD FOR WEED CONTROL IN LAWN BAYER CROPSCIENCE AG (DE) 2010-01-21 US disclosed
US-20100016158-A1 METHOD FOR WEED CONTROL IN LAWN BAYER CROPSCIENCE AG (DE) 2010-01-21 US disclosed
WO-2009103451-A1 HERBICIDE COMBINATIONS CONTAINING A HERBICIDE FROM THE CLASS OF DIAMINO-S-TRIAZINES BAYER CROPSCIENCE AG (DE) 2009-08-27 WO disclosed
EP-2092825-A1 Herbicidal combinations comprising a herbicide of the class of the diamino-s-triazines Bayer CropScience Aktiengesellschaft (DE) 2009-08-26 EP disclosed
EP-1958509-A1 Herbicide combination Bayer CropScience AG (DE) 2008-08-20 EP disclosed
EP-1854355-A1 Aqueous suspension concentrates Bayer CropScience AG (DE) 2007-11-14 EP disclosed
US-20070219095-A1 AQUEOUS SUSPENSION CONCENTRATES BAYER CROPSCIENCE GMBH (DE) 2007-09-20 US disclosed
US-20070123424-A1 AQUEOUS SUSPENSION CONCENTRATES BAYER CROPSCIENCE GMBH (DE) 2007-05-31 US disclosed
EP-1790227-A1 Aqueous suspension-concentrates of 2,4-diamino-s-triazine herbicides Bayer CropScience AG (DE) 2007-05-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100016158-A1 METHOD FOR WEED CONTROL IN LAWN NOTUM, RDX, WASF2 KDM4E 1113/4885GAA 843/4885L3MBTL1 304/4885
US-20070123424-A1 AQUEOUS SUSPENSION CONCENTRATES ASH2L, SPATS2L, AS3MT KDM4E 1181/4885GAA 3343/4885L3MBTL1 4057/4885
US-20070219095-A1 AQUEOUS SUSPENSION CONCENTRATES SLC43A1, AS3MT, SLC7A5 KDM4E 2316/4885GAA 810/4885L3MBTL1 1828/4885
US-20100048400-A1 HERBICIDE COMBINATION DDT, DRD1, DRD2 KDM4E 4476/4885GAA 1848/4885L3MBTL1 300/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.