Sugi Predict

Sugi Predict / Compounds / SCHEMBL1551697

SCHEMBL1551697

SCHEMBL1551697

Cc1ccc2c(c1)C(Nc1ncnc(N)n1)CC2

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RAB9A P51151 1/20 0.45
▸ KDM4E B2RXH2 1/20 0.39
▸ GAA P10253 1/20 0.39
▸ L3MBTL1 Q9Y468 1/20 0.39
▸ HTT P42858 1/20 0.37
▸ IDO1 P14902 1/20 0.36
▸ TRPV1 Q8NER1 1/20 0.36
▸ EGFR P00533 1/20 0.35
▸ JAK2 O60674 5/20 0.35
▸ JAK3 P52333 5/20 0.35
▸ JAK1 P23458 3/20 0.35
▸ TYK2 P29597 3/20 0.35
▸ BMX P51813 1/20 0.35
▸ BCL6 P41182 1/20 0.35
▸ SMN1; SMN2 Q16637 1/20 0.33
▸ IGF1R P08069 1/20 0.33
▸ ADORA3 P0DMS8 1/20 0.33
▸ SLC6A2 P23975 1/20 0.33
▸ PDE4A P27815 1/20 0.33
▸ KDR P35968 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1551809 1.00 RAB9A (0.45) RAB9AKDM4EGAAL3MBTL1HTT
SCHEMBL1551701 1.00 RAB9A (0.45) RAB9AKDM4EGAAL3MBTL1HTT
SCHEMBL11960134 0.93 RAB9A (0.43) RAB9AKDM4EGAAL3MBTL1HTT
SCHEMBL11960178 0.93 RAB9A (0.43) RAB9AKDM4EGAAL3MBTL1HTT
SCHEMBL1552534 0.85 SMN1; SMN2 (0.45) KDM4EGAAL3MBTL1IDO1JAK2
SCHEMBL1552536 0.85 SMN1; SMN2 (0.45) KDM4EGAAL3MBTL1IDO1JAK2
SCHEMBL1552560 0.85 SMN1; SMN2 (0.45) KDM4EGAAL3MBTL1IDO1JAK2
SCHEMBL1552577 0.85 KDM4E (0.44) RAB9AKDM4EGAAL3MBTL1HTT
SCHEMBL11960089 0.85 KDM4E (0.44) RAB9AKDM4EGAAL3MBTL1HTT
SCHEMBL1552576 0.85 KDM4E (0.44) RAB9AKDM4EGAAL3MBTL1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE47666-E1 Herbicidal compositions BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2019-10-29 — — US disclosed
US-RE46095-E1 Herbicidal compositions BAYER INTELLECTUAL PROPERTY GMBH (DE) 2016-08-09 — — US disclosed
US-RE46095-E1 Herbicidal compositions BAYER INTELLECTUAL PROPERTY GMBH (DE) 2016-08-09 — — US disclosed
US-8586503-B2 Herbicidal compositions BAYER CROPSCIENCE AG (DE) 2013-11-19 — — US disclosed
US-8426342-B2 Method for weed control in lawn BAYER CROPSCIENCE AG (DE) 2013-04-23 — — US disclosed
US-8426342-B2 Method for weed control in lawn BAYER CROPSCIENCE AG (DE) 2013-04-23 — — US disclosed
US-8236729-B2 Synergistic mixtures BAYER CROPSCIENCE AG (DE) 2012-08-07 — — US disclosed
US-8236729-B2 Synergistic mixtures BAYER CROPSCIENCE AG (DE) 2012-08-07 — — US disclosed
EP-2012588-B1 AQUEOUS SUSPENSION CONCENTRATE BAYER CROPSCIENCE AG (DE) 2011-04-27 — — EP disclosed
US-20100048399-A1 HERBICIDAL COMPOSITIONS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2010-02-25 — — US disclosed
US-20100048399-A1 HERBICIDAL COMPOSITIONS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2010-02-25 — — US disclosed
US-20100048400-A1 HERBICIDE COMBINATION BAYER CROPSCIENCE AG (DE) 2010-02-25 — — US disclosed
US-20100016158-A1 METHOD FOR WEED CONTROL IN LAWN BAYER CROPSCIENCE AG (DE) 2010-01-21 — — US disclosed
US-20100016158-A1 METHOD FOR WEED CONTROL IN LAWN BAYER CROPSCIENCE AG (DE) 2010-01-21 — — US disclosed
WO-2009103451-A1 HERBICIDE COMBINATIONS CONTAINING A HERBICIDE FROM THE CLASS OF DIAMINO-S-TRIAZINES BAYER CROPSCIENCE AG (DE) 2009-08-27 — — WO disclosed
EP-1958509-A1 Herbicide combination Bayer CropScience AG (DE) 2008-08-20 — — EP disclosed
EP-1854355-A1 Aqueous suspension concentrates Bayer CropScience AG (DE) 2007-11-14 — — EP disclosed
US-20070219095-A1 AQUEOUS SUSPENSION CONCENTRATES BAYER CROPSCIENCE GMBH (DE) 2007-09-20 — — US disclosed
US-20070123424-A1 AQUEOUS SUSPENSION CONCENTRATES BAYER CROPSCIENCE GMBH (DE) 2007-05-31 — — US disclosed
EP-1790227-A1 Aqueous suspension-concentrates of 2,4-diamino-s-triazine herbicides Bayer CropScience AG (DE) 2007-05-30 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100016158-A1 METHOD FOR WEED CONTROL IN LAWN NOTUM, RDX, WASF2 RAB9A 443/4885KDM4E 1113/4885GAA 843/4885
US-20070123424-A1 AQUEOUS SUSPENSION CONCENTRATES ASH2L, SPATS2L, AS3MT RAB9A 3690/4885KDM4E 1181/4885GAA 3343/4885
US-20100048399-A1 HERBICIDAL COMPOSITIONS KCNH1, HRH4, KCNH2 RAB9A 2782/4885KDM4E 1799/4885GAA 1577/4885
US-20070219095-A1 AQUEOUS SUSPENSION CONCENTRATES SLC43A1, AS3MT, SLC7A5 RAB9A 3979/4885KDM4E 2316/4885GAA 810/4885
US-20100048400-A1 HERBICIDE COMBINATION DDT, DRD1, DRD2 RAB9A 2191/4885KDM4E 4476/4885GAA 1848/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.