SCHEMBL15525880

SCHEMBL15525880

C[C]1C=Cc2c1cccc2-c1ccc(C)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 1/20 0.37
ENPP1 P22413 1/20 0.34
KDR P35968 1/20 0.34
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
POLB P06746 1/20 0.33
ACHE P22303 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
SYK P43405 1/20 0.33
RAB9A P51151 5/20 0.33
NPC1 O15118 4/20 0.33
CRHR1 P34998 1/20 0.32
LMNA P02545 2/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
NR2F2 P24468 1/20 0.32
HTT P42858 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1025199 0.73 CYP2A6 (0.38) MEN1KMT2APOLBACHERAB9A
SCHEMBL8036362 0.71 LMNA (0.50) MEN1KMT2APOLBACHETDP1
SCHEMBL28667587 0.71 CYP2A6 (0.36) MEN1KMT2APOLBACHERAB9A
SCHEMBL2969427 0.69 ADORA3 (0.39) ADORA3ENPP1MEN1KMT2APOLB
SCHEMBL1005237 0.69 MEN1 (0.46) ENPP1KDRMEN1KMT2APOLB
SCHEMBL12285691 0.69 ACHE (0.40) ADORA3ENPP1MEN1KMT2APOLB
SCHEMBL3175260 0.69 ENPP1 (0.41) ADORA3ENPP1MEN1KMT2APOLB
SCHEMBL26467874 0.69 ALDH1A1 (0.43) ADORA3ENPP1MEN1KMT2APOLB
SCHEMBL6318211 0.69 NPC1 (0.44) ADORA3ENPP1KDRMEN1KMT2A
SCHEMBL28947791 0.68 CA1 (0.33) ACHEALDH1A1CA2CA9TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013158411-A1 METHODS OF SEPARATING COMPOUNDS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-10-24 WO disclosed