Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 13/20 | 0.57 |
| ▸ | BCR | P11274 | 12/20 | 0.57 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15533974 | 0.90 | ABL1 (0.69) | ABL1BCRUSP2ALDH1A1CYP1A2 | |
| SCHEMBL15534389 | 0.79 | ABL1 (0.39) | ABL1BCRUSP2ALDH1A1CYP1A2 | |
| SCHEMBL15533795 | 0.79 | ABL1 (0.64) | ABL1BCRUSP2ALDH1A1CYP1A2 | |
| SCHEMBL15533691 | 0.77 | MAPT (0.47) | ABL1BCRUSP2ALDH1A1CYP1A2 | |
| SCHEMBL15534046 | 0.76 | ABL1 (0.68) | ABL1BCRUSP2ALDH1A1CYP1A2 | |
| SCHEMBL15533534 | 0.74 | THRB (0.58) | ABL1BCRLMNABACE1MAPT | |
| SCHEMBL5923911 | 0.74 | TRPV1 (0.56) | ABL1BCRUSP2ALDH1A1CYP1A2 | |
| SCHEMBL15534009 | 0.74 | MAPT (0.48) | ALDH1A1CYP1A2CYP2D6ALOX15CYP2C19 | |
| SCHEMBL12943132 | 0.73 | ABL1 (1.00) | ABL1BCRUSP2ALDH1A1CYP1A2 | |
| SCHEMBL15533631 | 0.73 | ABL1 (0.46) | ABL1BCRUSP2ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013175415-A1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AND USES THEREOF | Piramal Enterprises Limited (IN) | 2013-11-28 | — | — | WO | claimed |