Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 3/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 7/20 | 0.45 |
| ▸ | NPC1 | O15118 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TYK2 | P29597 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15536636 | 1.00 | HTR2B (0.50) | HTR2BMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL8515079 | 0.87 | ALDH1A1 (0.57) | MEN1KMT2AALDH1A1KDM4ERAB9A | |
| SCHEMBL15480774 | 0.87 | ALDH1A1 (0.57) | MEN1KMT2AALDH1A1KDM4ERAB9A | |
| SCHEMBL15535350 | 0.87 | ALDH1A1 (0.57) | MEN1KMT2AALDH1A1KDM4ERAB9A | |
| SCHEMBL15476462 | 0.87 | ALDH1A1 (0.57) | MEN1KMT2AALDH1A1KDM4ERAB9A | |
| SCHEMBL15480784 | 0.87 | ALDH1A1 (0.57) | MEN1KMT2AALDH1A1KDM4ERAB9A | |
| SCHEMBL15534635 | 0.87 | ALDH1A1 (0.57) | MEN1KMT2AALDH1A1KDM4ERAB9A | |
| SCHEMBL15606278 | 0.83 | KLK1 (0.38) | MEN1KMT2AKDM4ERXFP1EPHX2 | |
| SCHEMBL17131952 | 0.79 | NPC1 (0.72) | HTR2BMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL15480781 | 0.77 | TAS1R3 (0.50) | MEN1KMT2AALDH1A1KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9458174-B2 | Inhibitors of the activity of complex (III) of the mitochondrial electron transport chain and use thereof | STEMERGIE BIOTECHNOLOGY SA (CH) | 2016-10-04 | — | — | US | disclosed |
| US-9458174-B2 | Inhibitors of the activity of complex (III) of the mitochondrial electron transport chain and use thereof | STEMERGIE BIOTECHNOLOGY SA (CH) | 2016-10-04 | — | — | US | disclosed |
| US-20150148301-A1 | INHIBITORS OF THE ACTIVITY OF COMPLEX (III) OF THE MITOCHONDRIAL ELECTRON TRANSPORT CHAIN AND USE THEREOF | Stemergie Biotechnology SA a corporation | 2015-05-28 | — | — | US | disclosed |
| US-20150148301-A1 | INHIBITORS OF THE ACTIVITY OF COMPLEX (III) OF THE MITOCHONDRIAL ELECTRON TRANSPORT CHAIN AND USE THEREOF | Stemergie Biotechnology SA a corporation | 2015-05-28 | — | — | US | disclosed |
| EP-2852439-A1 | INHIBITORS OF THE ACTIVITY OF COMPLEX (III) OF THE MITOCHONDRIAL ELECTRON TRANSPORT CHAIN AND USE THEREOF | Stemergie Biotechnology SA (CH) | 2015-04-01 | — | — | EP | disclosed |
| WO-2013174947-A1 | INHIBITORS OF THE ACTIVITY OF COMPLEX (III) OF THE MITOCHONDRIAL ELECTRON TRANSPORT CHAIN AND USE THEREOF | STEMERGIE BIOTECHNOLOGY SA (CH) | 2013-11-28 | — | — | WO | disclosed |
| WO-2013174947-A1 | INHIBITORS OF THE ACTIVITY OF COMPLEX (III) OF THE MITOCHONDRIAL ELECTRON TRANSPORT CHAIN AND USE THEREOF | STEMERGIE BIOTECHNOLOGY SA (CH) | 2013-11-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150148301-A1 | INHIBITORS OF THE ACTIVITY OF COMPLEX (III) OF THE MITOCHONDRIAL ELECTRON TRANSPORT CHAIN AND USE THEREOF | NDUFB3, MT-CO3, SLC25A1 | HTR2B 4751/4885MEN1 2932/4885KMT2A 3571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.