Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 10/20 | 0.43 |
| ▸ | BCR | P11274 | 9/20 | 0.43 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 3/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.39 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.38 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15533228 | 0.89 | ABL1 (0.44) | ABL1BCRTAS2R14SYKKDM4E | |
| SCHEMBL15533691 | 0.87 | MAPT (0.47) | ABL1BCRKDM4EMAPTMAPK1 | |
| SCHEMBL15534453 | 0.81 | TAS2R14 (0.47) | ABL1BCRTAS2R14SYKMAPT | |
| SCHEMBL15533972 | 0.80 | ABL1 (0.53) | ABL1BCRSYKKDM4EMAPT | |
| SCHEMBL15533969 | 0.78 | CYP1A1 (0.48) | ABL1BCRSYKMAPK1 | |
| SCHEMBL15534290 | 0.78 | ABL1 (0.46) | ABL1BCRTAS2R14SYKKDM4E | |
| SCHEMBL15534101 | 0.78 | TRPV1 (0.47) | ABL1BCRTAS2R14KDM4EMAPT | |
| SCHEMBL15533991 | 0.78 | MAPT (0.63) | ABL1BCRSYKKDM4EMAPT | |
| Bromide SCHEMBL15534396 | 0.77 | TRPV1 (0.47) | ABL1BCRTAS2R14KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL15533549 | 0.77 | TRPV1 (0.47) | ABL1BCRTAS2R14KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013177092-A1 | SUBSTITUTED ALKYNYL PYRIDINE COMPOUNDS AND METHODS OF USE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2013-11-28 | — | — | WO | disclosed |