Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | TP53 | P04637 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15534734 | 0.87 | ABL1 (0.43) | MAPTKDM4EABL1BCRMAPK1 | |
| SCHEMBL15533972 | 0.86 | ABL1 (0.53) | MAPTTP53SMN1; SMN2KDM4EABL1 | |
| SCHEMBL15533969 | 0.84 | CYP1A1 (0.48) | HPGDHSD17B10LMNATP53SMN1; SMN2 | |
| SCHEMBL15534101 | 0.81 | TRPV1 (0.47) | MAPTTP53KMT2AKDM4EABL1 | |
| SCHEMBL15533965 | 0.81 | SYK (0.51) | MAPTHPGDHSD17B10LMNATP53 | |
| SCHEMBL15534259 | 0.81 | TRPV1 (0.57) | ABL1BCR | |
| SCHEMBL15533871 | 0.81 | TP53 (0.51) | MAPTHSD17B10LMNATP53KMT2A | |
| Bromide SCHEMBL15534396 | 0.81 | TRPV1 (0.47) | MAPTTP53KMT2AKDM4EABL1 | |
| Hydrochloric Acid SCHEMBL15533549 | 0.81 | TRPV1 (0.47) | MAPTTP53KMT2AKDM4EABL1 | |
| SCHEMBL15533818 | 0.81 | CYP2D6 (0.50) | MAPTHSD17B10LMNATP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013175415-A1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AND USES THEREOF | Piramal Enterprises Limited (IN) | 2013-11-28 | — | — | WO | disclosed |