Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | EGLN3 | Q9H6Z9 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15535827 | 0.89 | SMN1; SMN2 (0.45) | RAB9ASMN1; SMN2PKMKMT2AMEN1 | |
| SCHEMBL15535476 | 0.83 | P2RX3 (0.44) | RAB9ASMN1; SMN2PKMKMT2AMEN1 | |
| SCHEMBL15536589 | 0.78 | NPSR1 (0.41) | RAB9ASMN1; SMN2PKMKMT2AMEN1 | |
| SCHEMBL3421192 | 0.76 | EGLN3 (0.69) | L3MBTL1EGLN3KDM4ELMNA | |
| SCHEMBL15535643 | 0.73 | ALDH1A1 (0.37) | SMN1; SMN2KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL15536738 | 0.70 | OGFOD1 (0.38) | SMN1; SMN2KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL15536009 | 0.69 | EGLN3 (0.37) | RAB9ASMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL26214647 | 0.69 | ALDH1A1 (0.75) | RAB9ASMN1; SMN2PKMKMT2AMEN1 | |
| SCHEMBL15536586 | 0.69 | C5AR1 (0.44) | KMT2AMEN1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL3419394 | 0.68 | EGLN3 (0.66) | RAB9ASMN1; SMN2PKMKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013177478-A2 | TREATMENT METHOD | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2013-11-28 | — | — | WO | disclosed |