Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.44 |
| ▸ | EGLN3 | Q9H6Z9 | 4/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.41 |
| ▸ | EGLN2 | Q96KS0 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | GNRHR | P30968 | 2/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15535650 | 0.83 | RAB9A (0.46) | EGLN3HDAC1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL15535827 | 0.80 | SMN1; SMN2 (0.45) | EGLN3SMN1; SMN2KDM4EALDH1A1RAB9A | |
| SCHEMBL3420498 | 0.79 | EGLN3 (0.66) | EGLN3HDAC1HDAC8HDAC6HDAC11 | |
| SCHEMBL15536589 | 0.74 | NPSR1 (0.41) | EGLN3EGLN1EGLN2SMN1; SMN2ALDH1A1 | |
| SCHEMBL15536009 | 0.71 | EGLN3 (0.37) | EGLN3EGLN1EGLN2SMN1; SMN2KDM4E | |
| SCHEMBL9977540 | 0.68 | P2RX3 (0.56) | P2RX3HDAC1HDAC8HDAC6HDAC11 | |
| SCHEMBL1946028 | 0.67 | MEN1 (0.57) | SMN1; SMN2KDM4EALDH1A1CFTRRAB9A | |
| SCHEMBL15536738 | 0.66 | OGFOD1 (0.38) | P2RX3EGLN3EGLN1EGLN2SMN1; SMN2 | |
| Dl-Phenylalanine SCHEMBL28313877 | 0.66 | SLC7A5 (0.71) | KDM4EPKMHIF1A | |
| SCHEMBL1948009 | 0.65 | ADORA3 (0.52) | P2RX3SMN1; SMN2CFTRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013177478-A2 | TREATMENT METHOD | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2013-11-28 | — | — | WO | disclosed |