Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | NPC1 | O15118 | 4/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | GFER | P55789 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | HTR2B | P41595 | 1/20 | 0.57 |
| ▸ | ERN1 | O75460 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | KDM1A | O60341 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.52 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6707186 | 0.83 | RAB9A (0.79) | RAB9ANPC1L3MBTL1SMN1; SMN2PKM | |
| SCHEMBL9265040 | 0.83 | RAB9A (0.79) | RAB9ANPC1L3MBTL1SMN1; SMN2PKM | |
| SCHEMBL13105707 | 0.83 | RAB9A (0.69) | RAB9ANPC1L3MBTL1SMN1; SMN2PKM | |
| SCHEMBL4262114 | 0.82 | RAB9A (0.63) | RAB9ANPC1L3MBTL1SMN1; SMN2PKM | |
| SCHEMBL25843275 | 0.81 | NPC1 (0.59) | RAB9ANPC1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL24166611 | 0.81 | NPC1 (0.62) | RAB9ANPC1L3MBTL1SMN1; SMN2PKM | |
| SCHEMBL22930836 | 0.80 | NPC1 (0.58) | RAB9ANPC1L3MBTL1SMN1; SMN2PKM | |
| SCHEMBL19445791 | 0.79 | RAB9A (0.72) | RAB9ANPC1L3MBTL1SMN1; SMN2PKM | |
| SCHEMBL20888434 | 0.78 | L3MBTL1 (0.60) | RAB9ANPC1L3MBTL1SMN1; SMN2PKM | |
| SCHEMBL12852598 | 0.78 | RAB9A (0.62) | RAB9ANPC1L3MBTL1SMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9458174-B2 | Inhibitors of the activity of complex (III) of the mitochondrial electron transport chain and use thereof | STEMERGIE BIOTECHNOLOGY SA (CH) | 2016-10-04 | — | — | US | disclosed |
| US-9458174-B2 | Inhibitors of the activity of complex (III) of the mitochondrial electron transport chain and use thereof | STEMERGIE BIOTECHNOLOGY SA (CH) | 2016-10-04 | — | — | US | disclosed |
| US-20150148301-A1 | INHIBITORS OF THE ACTIVITY OF COMPLEX (III) OF THE MITOCHONDRIAL ELECTRON TRANSPORT CHAIN AND USE THEREOF | Stemergie Biotechnology SA a corporation | 2015-05-28 | — | — | US | disclosed |
| US-20150148301-A1 | INHIBITORS OF THE ACTIVITY OF COMPLEX (III) OF THE MITOCHONDRIAL ELECTRON TRANSPORT CHAIN AND USE THEREOF | Stemergie Biotechnology SA a corporation | 2015-05-28 | — | — | US | disclosed |
| EP-2852439-A1 | INHIBITORS OF THE ACTIVITY OF COMPLEX (III) OF THE MITOCHONDRIAL ELECTRON TRANSPORT CHAIN AND USE THEREOF | Stemergie Biotechnology SA (CH) | 2015-04-01 | — | — | EP | disclosed |
| WO-2013174947-A1 | INHIBITORS OF THE ACTIVITY OF COMPLEX (III) OF THE MITOCHONDRIAL ELECTRON TRANSPORT CHAIN AND USE THEREOF | STEMERGIE BIOTECHNOLOGY SA (CH) | 2013-11-28 | — | — | WO | disclosed |
| WO-2013174947-A1 | INHIBITORS OF THE ACTIVITY OF COMPLEX (III) OF THE MITOCHONDRIAL ELECTRON TRANSPORT CHAIN AND USE THEREOF | STEMERGIE BIOTECHNOLOGY SA (CH) | 2013-11-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150148301-A1 | INHIBITORS OF THE ACTIVITY OF COMPLEX (III) OF THE MITOCHONDRIAL ELECTRON TRANSPORT CHAIN AND USE THEREOF | NDUFB3, MT-CO3, SLC25A1 | RAB9A 2795/4885NPC1 825/4885L3MBTL1 4262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.