Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.57 |
| ▸ | FPR2 | P25090 | 2/20 | 0.53 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3405447 | 0.87 | KDM4E (0.47) | SLC6A2SLC6A4SLC6A3FPR2PROKR1 | |
| SCHEMBL15537475 | 0.86 | SLC6A4 (0.52) | SLC6A2SLC6A4SLC6A3FPR2PROKR1 | |
| SCHEMBL15536845 | 0.84 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3FPR2PROKR1 | |
| SCHEMBL15536002 | 0.77 | FPR2 (0.47) | FPR2PROKR1OPRD1KDM4ECACNA2D1 | |
| SCHEMBL16657611 | 0.76 | SLC6A4 (0.73) | SLC6A2SLC6A4SLC6A3FPR2PROKR1 | |
| SCHEMBL4072569 | 0.76 | OPRD1 (0.46) | OPRD1CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL10335593 | 0.75 | SLC6A4 (0.47) | SLC6A2SLC6A4SLC6A3FPR2PROKR1 | |
| SCHEMBL23211957 | 0.73 | CACNA1B (0.42) | SLC6A3CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL21381670 | 0.73 | CACNA1B (0.42) | SLC6A3CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL7086566 | 0.73 | FPR2 (0.50) | FPR2PROKR1ALDH1A1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2855449-A1 | SULFONYL PIPERIDINE DERIVATIVES AND THEIR USE FOR TREATING PROKINETICIN MEDIATED DISEASES | Takeda Pharmaceutical Company Limited (JP) | 2015-04-08 | — | — | EP | disclosed |
| WO-2013179024-A1 | SULFONYL PIPERIDINE DERIVATIVES AND THEIR USE FOR TREATING PROKINETICIN MEDIATED DISEASES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-12-05 | — | — | WO | disclosed |