Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.52 |
| ▸ | FPR2 | P25090 | 4/20 | 0.51 |
| ▸ | PROKR1 | Q8TCW9 | 4/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7086566 | 0.87 | FPR2 (0.50) | FPR2PROKR1MGLL | |
| SCHEMBL15535962 | 0.86 | SLC6A2 (0.57) | SLC6A4FPR2PROKR1OPRD1CACNA2D1 | |
| SCHEMBL23212057 | 0.86 | CACNA1B (0.43) | FPR2PROKR1CACNA2D1CACNA1BCACNB1 | |
| SCHEMBL13591106 | 0.83 | ALDH1A1 (0.53) | SLC6A4FPR2PROKR1MAPT | |
| SCHEMBL3405447 | 0.81 | KDM4E (0.47) | SLC6A4FPR2PROKR1OPRD1CACNA2D1 | |
| SCHEMBL15536002 | 0.80 | FPR2 (0.47) | FPR2PROKR1OPRD1CACNA2D1CACNA1B | |
| SCHEMBL4072569 | 0.78 | OPRD1 (0.46) | OPRD1CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL28086941 | 0.75 | DPP4 (0.42) | MAPTMGLLDPP4DPP7 | |
| SCHEMBL15536288 | 0.75 | FPR2 (0.49) | FPR2PROKR1OPRD1CACNA2D1CACNA1B | |
| SCHEMBL13591158 | 0.75 | CYP3A4 (0.54) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2855449-A1 | SULFONYL PIPERIDINE DERIVATIVES AND THEIR USE FOR TREATING PROKINETICIN MEDIATED DISEASES | Takeda Pharmaceutical Company Limited (JP) | 2015-04-08 | — | — | EP | disclosed |
| WO-2013179024-A1 | SULFONYL PIPERIDINE DERIVATIVES AND THEIR USE FOR TREATING PROKINETICIN MEDIATED DISEASES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-12-05 | — | — | WO | disclosed |