Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21333447 | 0.74 | CYP2A6 (0.39) | ERN1CYP2A6PTPN1PLAUPIM1 | |
| SCHEMBL2092077 | 0.71 | CYP2A6 (0.37) | ERN1CYP2A6ALDH1A1KDM4EMEN1 | |
| SCHEMBL7633234 | 0.69 | PIM1 (0.45) | ERN1TSHRCYP2A6PIM1ALDH1A1 | |
| SCHEMBL11684409 | 0.68 | MAOA (0.43) | ERN1CYP2A6PIM1ALDH1A1MEN1 | |
| SCHEMBL23271180 | 0.67 | ALDH1A1 (0.41) | CA1CA2TSHRPTPN1PIM1 | |
| Magnesium Chloride Anhydrous SCHEMBL20694938 | 0.67 | CA4 (0.32) | CA1CA2TSHRCYP2A6ALDH1A1 | |
| SCHEMBL27488106 | 0.67 | APAF1 (0.36) | CYP2A6MEN1MAPTKMT2ALMNA | |
| SCHEMBL10966532 | 0.65 | TAAR1 (0.33) | ERN1TSHRPLAUPIM1ALDH1A1 | |
| SCHEMBL16553301 | 0.64 | CYP2A6 (0.43) | ERN1CA1CA2TSHRCYP2A6 | |
| SCHEMBL10902490 | 0.63 | KMT2A (0.43) | PLAUALDH1A1KDM4EMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732102-B2 | System for controlling the reactivity of boronic acids | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2017-08-15 | — | — | US | disclosed |
| US-20170002026-A1 | System for Controlling the Reactivity of Boronic Acids | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2017-01-05 | — | — | US | disclosed |
| US-9328127-B2 | System for controlling the reactivity of boronic acids | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2016-05-03 | — | — | US | disclosed |
| EP-2181103-B1 | SYSTEM FOR CONTROLLING THE REACTIVITY OF BORONIC ACIDS | UNIV ILLINOIS (US) | 2015-08-05 | — | — | EP | disclosed |
| US-20130296573-A1 | System for Controlling the Reactivity of Boronic Acids | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2013-11-07 | — | — | US | disclosed |
| US-8318983-B2 | System for controlling the reactivity of boronic acids | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2012-11-27 | — | — | US | disclosed |
| US-20120059184-A1 | System for Controlling the Reactivity of Boronic Acids | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2012-03-08 | — | — | US | disclosed |
| US-8013203-B2 | System for controlling the reactivity of boronic acids | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2011-09-06 | — | — | US | disclosed |
| EP-2181103-A1 | SYSTEM FOR CONTROLLING THE REACTIVITY OF BORONIC ACIDS | The Board Of Trustees Of The University Of Illinois (US) | 2010-05-05 | — | — | EP | disclosed |
| WO-2009014550-A1 | SYSTEM FOR CONTROLLING THE REACTIVITY OF BORONIC ACIDS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2009-01-29 | — | — | WO | disclosed |
| US-20090030238-A1 | SYSTEM FOR CONTROLLING THE REACTIVITY OF BORONIC ACIDS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170002026-A1 | System for Controlling the Reactivity of Boronic Acids | ORC3, BRS3, OSBPL3 | ERN1 1716/4885CA1 647/4885CA2 415/4885 |
| US-20120059184-A1 | System for Controlling the Reactivity of Boronic Acids | ORC3, BRS3, OSBPL3 | ERN1 1716/4885CA1 647/4885CA2 415/4885 |
| US-20130296573-A1 | System for Controlling the Reactivity of Boronic Acids | ORC3, BRS3, OSBPL3 | ERN1 1716/4885CA1 647/4885CA2 415/4885 |
| US-20090030238-A1 | SYSTEM FOR CONTROLLING THE REACTIVITY OF BORONIC ACIDS | ORC3, BRS3, OSBPL3 | ERN1 1716/4885CA1 647/4885CA2 415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.