SCHEMBL27488106

SCHEMBL27488106

COc1occ2cc(Br)ccc12

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
APAF1 O14727 1/20 0.36
TDP2 O95551 1/20 0.36
POLB P06746 1/20 0.35
SMN1; SMN2 Q16637 4/20 0.34
RXFP1 Q9HBX9 2/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
MAPT P10636 1/20 0.34
LMNA P02545 4/20 0.33
CYP2A6 P11509 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
SIRT2 Q8IXJ6 2/20 0.33
PRNP P04156 1/20 0.33
NCEH1 Q6PIU2 1/20 0.33
ACHE P22303 1/20 0.32
FLT3 P36888 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10373029 0.79 CYP2A6 (0.45) POLBSMN1; SMN2MEN1KMT2AMAPT
SCHEMBL2092077 0.75 CYP2A6 (0.37) TDP2MEN1KMT2AMAPTLMNA
SCHEMBL21333447 0.74 CYP2A6 (0.39) TDP2MEN1KMT2AMAPTCYP2A6
SCHEMBL29529441 0.72 ALDH1A1 (0.41) POLBSMN1; SMN2MAPTCYP2A6
SCHEMBL10372643 0.68 CYP2A6 (0.45) POLBSMN1; SMN2MEN1KMT2AMAPT
SCHEMBL11684409 0.68 MAOA (0.43) SMN1; SMN2RXFP1MEN1KMT2AMAPT
SCHEMBL7629740 0.67 ERN1 (0.34) POLBRXFP1MEN1KMT2AMAPT
SCHEMBL155366 0.67 ERN1 (0.38) MEN1KMT2AMAPTLMNACYP2A6
SCHEMBL29815155 0.66 EIF4A1 (0.34) SMN1; SMN2MAPTLMNAL3MBTL1
SCHEMBL7633234 0.66 PIM1 (0.45) TDP2POLBRXFP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1182129-C Benzopyran derivatives having leukotriene-antagonistic action ������ʵ���ҹ�˾ 2004-12-29 CN disclosed
CN-1214048-A Benzopyran derivatives having leukotriene-antagonistic action LABROATORIOS MENARINI S A (ES) 1999-04-14 CN disclosed