SCHEMBL1553748

SCHEMBL1553748

CC(C)(Br)C(=O)c1ccc(Oc2ccccc2C(=O)C2CCCCC2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.44
MAPK1 P28482 3/20 0.44
KDM2B Q8NHM5 1/20 0.42
TSHR P16473 2/20 0.41
SCN1A P35498 1/20 0.41
SCN2A Q99250 1/20 0.41
SCN3A Q9NY46 1/20 0.41
POLB P06746 3/20 0.40
ELANE P08246 1/20 0.40
KDM4E B2RXH2 1/20 0.39
GAA P10253 2/20 0.39
MAPT P10636 3/20 0.39
THRB P10828 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
LMNA P02545 2/20 0.38
HSD11B1 P28845 1/20 0.38
KMT2A Q03164 1/20 0.38
SRD5A2 P31213 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1553746 0.85 ALDH1A1 (0.51) ALDH1A1MAPK1KDM2BPOLBGAA
SCHEMBL13283436 0.74 KDM2B (0.46) ALDH1A1KDM2BTSHRPOLBSMN1; SMN2
SCHEMBL6032432 0.73 ALDH1A1 (0.67) ALDH1A1MAPK1KDM2BPOLBELANE
SCHEMBL11877651 0.72 KDM2B (0.61) ALDH1A1MAPK1KDM2BPOLBGAA
SCHEMBL1554062 0.71 SRD5A2 (0.49) ALDH1A1POLBKDM4ELMNAKMT2A
SCHEMBL1553905 0.71 PARP10 (0.56) ALDH1A1POLBMAPTSMN1; SMN2LMNA
SCHEMBL29096232 0.71 ALDH1A1 (0.56) ALDH1A1MAPK1KDM2BTSHRPOLB
SCHEMBL4006142 0.71 CTNNB1 (0.46) SCN1ASCN2ASCN3AELANEKDM4E
SCHEMBL1446163 0.71 HPGD (0.56) ALDH1A1TSHRELANEMAPTSMN1; SMN2
SCHEMBL3629662 0.70 POLB (0.53) ALDH1A1MAPK1KDM2BTSHRPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1670740-B1 CLEAR PHOTOPOLYMERIZABLE SYSTEMS FOR THE PREPARATION OF HIGH THICKNESS COATINGS LAMBERTI SPA (IT) 2011-04-27 EP disclosed
US-7534880-B2 Clear photopolymerizable systems for the preparation of high thickness coatings LAMBERTI SPA (IT) 2009-05-19 US disclosed
US-20060246228-A1 Clear photopolymerizable systems for the preparation of high thickness coatings LAMBERTI SPA (IT) 2006-11-02 US disclosed
EP-1670740-A2 CLEAR PHOTOPOLYMERIZABLE SYSTEMS FOR THE PREPARATION OF HIGH THICKNESS COATINGS Lamberti Spa (IT) 2006-06-21 EP disclosed
WO-2005014515-A2 CLEAR PHOTOPOLYMERIZABLE SYSTEMS FOR THE PREPARATION OF HIGH THICKNESS COATINGS LAMBERTI SPA (IT) 2005-02-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060246228-A1 Clear photopolymerizable systems for the preparation of high thickness coatings CDH1, CLTA, VCL ALDH1A1 4625/4885MAPK1 4176/4885KDM2B 327/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.