SCHEMBL1553746

SCHEMBL1553746

CC(C)(Br)C(=O)c1ccc(Oc2ccc(C(=O)C3CCCCC3)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.51
MAPK1 P28482 2/20 0.51
SRD5A2 P31213 1/20 0.49
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
HRH3 Q9Y5N1 2/20 0.45
MAOB P27338 1/20 0.45
HRH2 P25021 1/20 0.45
HRH1 P35367 1/20 0.45
KDM2B Q8NHM5 5/20 0.43
LMNA P02545 2/20 0.43
GAA P10253 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
CHRM2 P08172 3/20 0.43
CHRM4 P08173 3/20 0.43
CHRM1 P11229 3/20 0.43
CHRM3 P20309 3/20 0.43
POLB P06746 1/20 0.43
MMP13 P45452 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1553748 0.85 ALDH1A1 (0.44) ALDH1A1MAPK1SRD5A2NPC1RAB9A
SCHEMBL1554062 0.82 SRD5A2 (0.49) ALDH1A1SRD5A2RAB9ALMNAL3MBTL1
SCHEMBL1446163 0.82 HPGD (0.56) ALDH1A1SRD5A2RAB9AMMP13
SCHEMBL6032432 0.81 ALDH1A1 (0.67) ALDH1A1MAPK1SRD5A2NPC1RAB9A
SCHEMBL9135757 0.78 NPC1 (0.75) ALDH1A1MAPK1SRD5A2NPC1RAB9A
SCHEMBL4611341 0.78 NPC1 (0.75) ALDH1A1MAPK1SRD5A2NPC1RAB9A
SCHEMBL9136904 0.76 NPC1 (0.77) ALDH1A1MAPK1SRD5A2NPC1RAB9A
SCHEMBL1553905 0.76 PARP10 (0.56) ALDH1A1SRD5A2NPC1RAB9ALMNA
SCHEMBL1553747 0.74 HPGD (0.38) ALDH1A1MAPK1RAB9AGAAMMP13
SCHEMBL3367257 0.73 NPC1 (0.77) ALDH1A1MAPK1NPC1RAB9AKDM2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1670740-B1 CLEAR PHOTOPOLYMERIZABLE SYSTEMS FOR THE PREPARATION OF HIGH THICKNESS COATINGS LAMBERTI SPA (IT) 2011-04-27 EP disclosed
US-7534880-B2 Clear photopolymerizable systems for the preparation of high thickness coatings LAMBERTI SPA (IT) 2009-05-19 US disclosed
US-20060246228-A1 Clear photopolymerizable systems for the preparation of high thickness coatings LAMBERTI SPA (IT) 2006-11-02 US disclosed
EP-1670740-A2 CLEAR PHOTOPOLYMERIZABLE SYSTEMS FOR THE PREPARATION OF HIGH THICKNESS COATINGS Lamberti Spa (IT) 2006-06-21 EP disclosed
WO-2005014515-A2 CLEAR PHOTOPOLYMERIZABLE SYSTEMS FOR THE PREPARATION OF HIGH THICKNESS COATINGS LAMBERTI SPA (IT) 2005-02-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060246228-A1 Clear photopolymerizable systems for the preparation of high thickness coatings CDH1, CLTA, VCL ALDH1A1 4625/4885MAPK1 4176/4885SRD5A2 4185/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.