SCHEMBL1554062

SCHEMBL1554062

CC(C)(Br)C(=O)c1ccc(Sc2ccc(C(=O)C3CCCCC3)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 1/20 0.49
MGLL Q99685 9/20 0.41
ALDH1A1 P00352 5/20 0.41
POLB P06746 1/20 0.41
RXFP1 Q9HBX9 1/20 0.41
HPGD P15428 2/20 0.40
RAB9A P51151 1/20 0.40
LMNA P02545 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
KDM4E B2RXH2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1553746 0.82 ALDH1A1 (0.51) SRD5A2ALDH1A1POLBRAB9ALMNA
SCHEMBL8630154 0.82 HPGD (0.56) ALDH1A1HPGDRAB9ALMNAL3MBTL1
SCHEMBL2993708 0.78 SRD5A2 (0.57) SRD5A2ALDH1A1POLBRXFP1LMNA
SCHEMBL1553692 0.76 HPGD (0.61) MGLLALDH1A1POLBHPGDLMNA
SCHEMBL6988277 0.76 ALDH1A1 (0.57) SRD5A2ALDH1A1POLBRXFP1LMNA
SCHEMBL1553898 0.74 HPGD (0.38) ALDH1A1HPGDLMNAL3MBTL1
SCHEMBL5187550 0.73 ALDH1A1 (0.57) SRD5A2ALDH1A1POLBRXFP1LMNA
SCHEMBL507614 0.72 KMT2A (0.66) SRD5A2MGLLALDH1A1POLBHPGD
SCHEMBL14335438 0.72 SRD5A2 (0.62) SRD5A2MGLLPOLBRAB9AMEN1
SCHEMBL26622715 0.72 SRD5A2 (0.62) SRD5A2MGLLPOLBRAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1670740-B1 CLEAR PHOTOPOLYMERIZABLE SYSTEMS FOR THE PREPARATION OF HIGH THICKNESS COATINGS LAMBERTI SPA (IT) 2011-04-27 EP disclosed
US-7534880-B2 Clear photopolymerizable systems for the preparation of high thickness coatings LAMBERTI SPA (IT) 2009-05-19 US disclosed
US-20060246228-A1 Clear photopolymerizable systems for the preparation of high thickness coatings LAMBERTI SPA (IT) 2006-11-02 US disclosed
EP-1670740-A2 CLEAR PHOTOPOLYMERIZABLE SYSTEMS FOR THE PREPARATION OF HIGH THICKNESS COATINGS Lamberti Spa (IT) 2006-06-21 EP disclosed
WO-2005014515-A2 CLEAR PHOTOPOLYMERIZABLE SYSTEMS FOR THE PREPARATION OF HIGH THICKNESS COATINGS LAMBERTI SPA (IT) 2005-02-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060246228-A1 Clear photopolymerizable systems for the preparation of high thickness coatings CDH1, CLTA, VCL SRD5A2 4185/4885MGLL 3387/4885ALDH1A1 4625/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.