SCHEMBL1553783

SCHEMBL1553783

CO[Si](CCCNC(=O)c1ccc(I)cc1)(OC)OC

nearest known ligand 0.57

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.57
NPC1 O15118 2/20 0.56
RAB9A P51151 2/20 0.56
DRD3 P35462 3/20 0.50
DRD2 P14416 2/20 0.50
POLB P06746 1/20 0.50
HPGD P15428 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
FOLH1 Q04609 7/20 0.47
KMT2A Q03164 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C9 P11712 1/20 0.47
DRD1 P21728 1/20 0.46
DRD4 P21917 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12891170 0.86 POLB (0.68) ALDH1A1NPC1RAB9APOLBHPGD
SCHEMBL2007944 0.84 NAAA (0.59) ALDH1A1NPC1RAB9APOLBHPGD
SCHEMBL2044554 0.84 ALDH1A1 (0.55) ALDH1A1NPC1RAB9APOLBHPGD
SCHEMBL4496407 0.82 HPGD (0.55) ALDH1A1NPC1RAB9ADRD3DRD2
SCHEMBL14890256 0.82 HDAC1 (0.62) ALDH1A1NPC1RAB9ADRD3DRD2
SCHEMBL18085336 0.82 ALDH1A1 (0.54) ALDH1A1NPC1RAB9APOLBHPGD
SCHEMBL9357695 0.80 MAPT (0.62) ALDH1A1NPC1RAB9ASMN1; SMN2KMT2A
SCHEMBL18782285 0.79 L3MBTL1 (0.63) ALDH1A1NPC1RAB9ASMN1; SMN2FOLH1
SCHEMBL13861935 0.78 DRD2 (0.63) ALDH1A1NPC1RAB9ADRD3DRD2
SCHEMBL1972791 0.78 NPC1 (0.49) ALDH1A1NPC1RAB9APOLBHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110159605-A1 Surface Grafted Conjugated Polymers UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2011-06-30 US claimed
WO-2008143731-A2 SURFACE GRAFTED CONJUGATED POLYMERS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2008-11-27 WO claimed
US-20160272768-A1 JOINED BODY JOINED BY CHEMICAL BONDING AT MATERIAL INTERFACE, AND JOINING METHOD FOR JOINED BODY OSAKA UNIVERSITY (JP) 2016-09-22 US disclosed
US-8598053-B2 Materials incorporating antimicrobial polymers STC.UNM (US) 2013-12-03 US disclosed
US-8455265-B2 Surface grafted conjugated polymers STC.UNM (US) 2013-06-04 US disclosed
US-20120271023-A1 MATERIALS INCORPORATING ANTIMICROBIAL POLYMERS STC.UNM (US) 2012-10-25 US disclosed
EP-2486184-A2 MATERIALS INCORPORATING ANTIMICROBIAL POLYMERS STC.UNM (US) 2012-08-15 EP disclosed
US-20110159605-A1 Surface Grafted Conjugated Polymers UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2011-06-30 US disclosed
WO-2011044580-A2 MATERIALS INCORPORATING ANTIMICROBIAL POLYMERS STC. UNM (US) 2011-04-14 WO disclosed
WO-2008143731-A2 SURFACE GRAFTED CONJUGATED POLYMERS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2008-11-27 WO disclosed