SCHEMBL4496407

SCHEMBL4496407

CO[Si](CCCNC(=O)c1ccc(C(=O)c2ccccc2)cc1)(OC)OC

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.55
ALDH1A1 P00352 3/20 0.54
NPC1 O15118 3/20 0.54
RAB9A P51151 3/20 0.54
NAAA Q02083 1/20 0.54
POLB P06746 2/20 0.53
LMNA P02545 2/20 0.53
KMT2A Q03164 1/20 0.51
DRD2 P14416 1/20 0.51
DRD3 P35462 1/20 0.51
HDAC3 O15379 1/20 0.50
HDAC4 P56524 1/20 0.50
HDAC1 Q13547 1/20 0.50
HDAC7 Q8WUI4 1/20 0.50
HDAC2 Q92769 1/20 0.50
HDAC10 Q969S8 1/20 0.50
HDAC11 Q96DB2 1/20 0.50
HDAC8 Q9BY41 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
HDAC9 Q9UKV0 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2007944 0.94 NAAA (0.59) HPGDALDH1A1NPC1RAB9ANAAA
SCHEMBL4501913 0.91 HPGD (0.57) HPGDALDH1A1NPC1RAB9ANAAA
SCHEMBL12927089 0.87 HDAC3 (0.50) HPGDALDH1A1NPC1RAB9ANAAA
SCHEMBL9980885 0.86 NAAA (0.55) HPGDALDH1A1NPC1RAB9ANAAA
SCHEMBL13861935 0.84 DRD2 (0.63) ALDH1A1NPC1RAB9ANAAADRD2
SCHEMBL12891170 0.84 POLB (0.68) HPGDALDH1A1NPC1RAB9APOLB
SCHEMBL1553783 0.82 ALDH1A1 (0.57) HPGDALDH1A1NPC1RAB9APOLB
SCHEMBL2044554 0.81 ALDH1A1 (0.55) HPGDALDH1A1NPC1RAB9APOLB
SCHEMBL16587877 0.81 SMN1; SMN2 (0.73) HPGDALDH1A1NPC1RAB9APOLB
SCHEMBL17835142 0.80 NAAA (0.76) HPGDALDH1A1NPC1RAB9ANAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070054127-A1 SILANE COATING COMPOSITIONS, COATING SYSTEMS, AND METHODS Surmodics Coatings, LLC 2007-03-08 US claimed
WO-2007025059-A1 SILANE COATING COMPOSITIONS, COATING SYSTEMS, AND METHODS SURMODICS, INC. (US) 2007-03-01 WO claimed
US-12599322-B2 Method for an analyte sensor cover-membrane preparation ROCHE DIABETES CARE, INC. (US) 2026-04-14 US disclosed
EP-3735903-B1 METHOD FOR AN ANALYTE SENSOR COVER-MEMBRANE PREPARATION ROCHE DIABETES CARE GMBH (DE) 2025-11-05 EP disclosed
EP-3359580-B1 POLYMER HAVING ANTIMICROBIAL AND/OR ANTIFOULING PROPERTIES UNIV FREIBURG ALBERT LUDWIGS (DE) 2022-03-30 EP disclosed
US-20220054059-A1 METHOD FOR AN ANALYTE SENSOR COVER-MEMBRANE PREPARATION ROCHE DIABETES CARE, INC. 2022-02-24 US disclosed
US-10889726-B2 Polymer having antimicrobial and/or antifouling properties ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) 2021-01-12 US disclosed
WO-2020225190-A1 METHOD FOR AN ANALYTE SENSOR COVER-MEMBRANE PREPARATION F. HOFFMANN-LA ROCHE AG (CH) 2020-11-12 WO disclosed
EP-3735903-A1 METHOD FOR AN ANALYTE SENSOR COVER-MEMBRANE PREPARATION Roche Diabetes Care GmbH (DE) 2020-11-11 EP disclosed
EP-2822986-B1 SYNTHESIS AND MICRO-/NANOSTRUCTURING OF SURFACE-ATTACHED CROSSLINKED ANTIMICROBIAL AND/OR ANTIBIOFOULING POLYMER NETWORKS UNIV FREIBURG (DE) 2019-10-30 EP disclosed
US-20190313642-A1 A SIMULTANEOUSLY ANTIMICROBIAL AND PROTEIN-REPELLENT POLYZWITTERION ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) 2019-10-17 US disclosed
WO-2012089617-A1 COVALENTLY ATTACHED ANTIMICROBIAL POLYMERS Universitätsklinikum Freiburg (DE) 2012-07-05 WO disclosed
EP-2471827-A1 Covalently attached antimicrobial polymers Universitätsklinikum Freiburg (DE) 2012-07-04 EP disclosed
US-20120148852-A1 SILANE COATING COMPOSITIONS, COATING SYSTEMS, AND METHODS SURMODICS, INC. (US) 2012-06-14 US disclosed
US-20110306722-A1 SURFACE-MODIFIED POLYMER FILMS BAR-ILAN UNIVERSITY (IL) 2011-12-15 US disclosed
EP-2117728-A2 SILANE COATING COMPOSITIONS, COATING SYSTEMS, AND METHODS SurModics, Inc. (US) 2009-11-18 EP disclosed
WO-2008103668-A2 SILANE COATING COMPOSITIONS, COATING SYSTEMS, AND METHODS SURMODICS, INC. (US) 2008-08-28 WO disclosed
US-20070141365-A1 Silane Coating Compositions, Coating Systems, and Methods Surmodics Coatings, LLC 2007-06-21 US disclosed
US-20070054127-A1 SILANE COATING COMPOSITIONS, COATING SYSTEMS, AND METHODS Surmodics Coatings, LLC 2007-03-08 US disclosed
WO-2007025059-A1 SILANE COATING COMPOSITIONS, COATING SYSTEMS, AND METHODS SURMODICS, INC. (US) 2007-03-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12599322-B2 Method for an analyte sensor cover-membrane preparation F10, S100A10, EPCAM HPGD 655/4885ALDH1A1 1382/4885NPC1 4536/4885
US-20190313642-A1 A SIMULTANEOUSLY ANTIMICROBIAL AND PROTEIN-REPELLENT POLYZWITTERION CUTA, WIZ, PUF60 HPGD 4429/4885ALDH1A1 4610/4885NPC1 3571/4885
US-20110306722-A1 SURFACE-MODIFIED POLYMER FILMS PARN, ITGAM, PARG HPGD 2579/4885ALDH1A1 3625/4885NPC1 4360/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.