SCHEMBL1553898

SCHEMBL1553898

CC(C)(Br)C(=O)c1ccc(Sc2ccc(C(=O)C3(Br)CCCCC3)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.38
LMNA P02545 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
RXRA P19793 2/20 0.35
RXRB P28702 2/20 0.35
RXRG P48443 2/20 0.35
RARB P10826 1/20 0.35
RARG P13631 1/20 0.35
ALDH1A1 P00352 2/20 0.34
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
OPRM1 P35372 1/20 0.32
OPRD1 P41143 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1553747 0.83 HPGD (0.38) HPGDRXRARXRBRXRGALDH1A1
SCHEMBL4428057 0.82 OPRM1 (0.31) OPRM1OPRD1
SCHEMBL8630154 0.80 HPGD (0.56) HPGDLMNAL3MBTL1RXRARXRB
SCHEMBL726159 0.79 MEN1 (0.46) HPGDLMNAALDH1A1TSHRMAPK1
SCHEMBL1555398 0.75 HPGD (0.38) HPGDLMNAL3MBTL1RXRARXRB
SCHEMBL1554062 0.74 SRD5A2 (0.49) HPGDLMNAL3MBTL1ALDH1A1
SCHEMBL1553692 0.74 HPGD (0.61) HPGDLMNAL3MBTL1ALDH1A1MAPK1
SCHEMBL4611297 0.71 GSK3B (0.51) HPGDLMNAL3MBTL1ALDH1A1MAPK1
SCHEMBL1446377 0.70 AKR1C1 (0.42) HPGDLMNAALDH1A1TSHR
SCHEMBL727190 0.69 HTT (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1670740-B1 CLEAR PHOTOPOLYMERIZABLE SYSTEMS FOR THE PREPARATION OF HIGH THICKNESS COATINGS LAMBERTI SPA (IT) 2011-04-27 EP disclosed
US-7534880-B2 Clear photopolymerizable systems for the preparation of high thickness coatings LAMBERTI SPA (IT) 2009-05-19 US disclosed
US-20060246228-A1 Clear photopolymerizable systems for the preparation of high thickness coatings LAMBERTI SPA (IT) 2006-11-02 US disclosed
EP-1670740-A2 CLEAR PHOTOPOLYMERIZABLE SYSTEMS FOR THE PREPARATION OF HIGH THICKNESS COATINGS Lamberti Spa (IT) 2006-06-21 EP disclosed
WO-2005014515-A2 CLEAR PHOTOPOLYMERIZABLE SYSTEMS FOR THE PREPARATION OF HIGH THICKNESS COATINGS LAMBERTI SPA (IT) 2005-02-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060246228-A1 Clear photopolymerizable systems for the preparation of high thickness coatings CDH1, CLTA, VCL HPGD 3253/4885LMNA 1005/4885L3MBTL1 4802/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.