SCHEMBL1553747

SCHEMBL1553747

CC(C)(Br)C(=O)c1ccc(Oc2ccc(C(=O)C3(Br)CCCCC3)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.38
MAPT P10636 1/20 0.38
RAB9A P51151 1/20 0.38
PARP10 Q53GL7 2/20 0.36
RXRA P19793 1/20 0.36
RXRB P28702 1/20 0.36
RXRG P48443 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
ALDH1A1 P00352 4/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
ELANE P08246 1/20 0.35
TSHR P16473 1/20 0.35
HTT P42858 1/20 0.35
KMT2A Q03164 3/20 0.34
PARP15 Q460N3 1/20 0.34
PARP14 Q460N5 1/20 0.34
PARP16 Q8N5Y8 1/20 0.34
PARP11 Q9NR21 1/20 0.34
PARP4 Q9UKK3 1/20 0.34
TP53 P04637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1553898 0.83 HPGD (0.38) HPGDRXRARXRBRXRGALDH1A1
SCHEMBL4428057 0.82 OPRM1 (0.31)
SCHEMBL4611297 0.81 GSK3B (0.51) HPGDMAPTRAB9APARP10ALDH1A1
SCHEMBL1446163 0.80 HPGD (0.56) HPGDMAPTRAB9APARP10ALDH1A1
SCHEMBL1553902 0.75 HPGD (0.38) HPGDMAPTRAB9APARP10RXRA
SCHEMBL1553746 0.74 ALDH1A1 (0.51) RAB9AALDH1A1MAPK1MMP13GAA
SCHEMBL1553905 0.74 PARP10 (0.56) HPGDMAPTRAB9APARP10ALDH1A1
SCHEMBL10458127 0.71 CES2 (0.59) MAPTRAB9APARP10ALDH1A1ELANE
SCHEMBL1446377 0.70 AKR1C1 (0.42) HPGDALDH1A1TSHRHTTKMT2A
SCHEMBL726159 0.70 MEN1 (0.46) HPGDMAPTRAB9AALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1670740-B1 CLEAR PHOTOPOLYMERIZABLE SYSTEMS FOR THE PREPARATION OF HIGH THICKNESS COATINGS LAMBERTI SPA (IT) 2011-04-27 EP disclosed
US-7534880-B2 Clear photopolymerizable systems for the preparation of high thickness coatings LAMBERTI SPA (IT) 2009-05-19 US disclosed
US-20060246228-A1 Clear photopolymerizable systems for the preparation of high thickness coatings LAMBERTI SPA (IT) 2006-11-02 US disclosed
EP-1670740-A2 CLEAR PHOTOPOLYMERIZABLE SYSTEMS FOR THE PREPARATION OF HIGH THICKNESS COATINGS Lamberti Spa (IT) 2006-06-21 EP disclosed
WO-2005014515-A2 CLEAR PHOTOPOLYMERIZABLE SYSTEMS FOR THE PREPARATION OF HIGH THICKNESS COATINGS LAMBERTI SPA (IT) 2005-02-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060246228-A1 Clear photopolymerizable systems for the preparation of high thickness coatings CDH1, CLTA, VCL HPGD 3253/4885MAPT 420/4885RAB9A 1158/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.