SCHEMBL15539031

SCHEMBL15539031

CCCC[C@@H]([C]=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(C)=O

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CTSS P25774 3/20 0.49
ALDH1A1 P00352 2/20 0.45
MMP3 P08254 6/20 0.39
MMP9 P14780 5/20 0.39
BIRC2 Q13490 2/20 0.38
CTSL P07711 1/20 0.38
CTSK P43235 1/20 0.38
BACE1 P56817 2/20 0.37
SIRT6 Q8N6T7 1/20 0.36
SIRT1 Q96EB6 1/20 0.36
MMP1 P03956 2/20 0.36
PLA2G2A P14555 2/20 0.36
PLA2G5 P39877 2/20 0.36
MMP2 P08253 1/20 0.36
MMP8 P22894 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3834367 0.84 ALDH1A1 (0.55) CTSSALDH1A1MMP9CTSLCTSK
SCHEMBL3365403 0.84 ALDH1A1 (0.55) CTSSALDH1A1MMP9CTSLCTSK
SCHEMBL21387168 0.82 ALDH1A1 (0.50) CTSSALDH1A1MMP3MMP9BIRC2
SCHEMBL3923432 0.82 CTSB (0.49) CTSSALDH1A1CTSKBACE1
SCHEMBL10378726 0.81 NPY4R (0.46) ALDH1A1
SCHEMBL10378723 0.81 NPY4R (0.46) ALDH1A1
SCHEMBL3426049 0.81 ALDH1A1 (0.62) ALDH1A1MMP3MMP9SIRT6SIRT1
SCHEMBL7114227 0.81 ALDH1A1 (0.62) ALDH1A1MMP3MMP9SIRT6SIRT1
SCHEMBL3426060 0.81 ALDH1A1 (0.62) ALDH1A1MMP3MMP9SIRT6SIRT1
SCHEMBL3381459 0.81 ALDH1A1 (0.62) ALDH1A1MMP3MMP9SIRT6SIRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11266968-B2 Mineralizing biosurfactant used for nucleating silica THE UNIVERSITY OF QUEENSLAND (AU) 2022-03-08 US disclosed
EP-3046870-B1 SILICA MICRO- AND NANO-CAPSULES AND METHODS FOR MAKING THEM UNIV QUEENSLAND (AU) 2021-08-11 EP disclosed
EP-2861217-B1 NANOEMULSIONS UNIV QUEENSLAND (AU) 2017-09-06 EP disclosed
US-9554995-B2 Nanoemulsions THE UNIVERSITY OF QUEENSLAND (AU) 2017-01-31 US disclosed
US-20160193581-A1 SILICA MICRO- AND NANO-CAPSULES AND METHODS FOR MAKING THEM THE UNIVERSITY OF QUEENSLAND (AU) 2016-07-07 US disclosed
US-20150132395-A1 NANOEMULSIONS THE UNIVERSITY OF QUEENSLAND (AU) 2015-05-14 US disclosed
EP-2861217-A1 NANOEMULSIONS The University Of Queensland (AU) 2015-04-22 EP disclosed
WO-2013185178-A1 NANOEMULSIONS THE UNIVERSITY OF QUEENSLAND (AU) 2013-12-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160193581-A1 SILICA MICRO- AND NANO-CAPSULES AND METHODS FOR MAKING THEM SGMS2, SGMS1, PHOSPHO1 CTSS 160/4885ALDH1A1 4682/4885MMP3 3576/4885
US-20150132395-A1 NANOEMULSIONS LNPEP, IAPP, CETP CTSS 1699/4885ALDH1A1 4632/4885MMP3 1639/4885
US-11266968-B2 Mineralizing biosurfactant used for nucleating silica SGMS2, PHOSPHO1, SOST CTSS 441/4885ALDH1A1 4784/4885MMP3 3284/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.