Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.34 |
| ▸ | FEN1 | P39748 | 3/20 | 0.34 |
| ▸ | HPGDS | O60760 | 4/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.33 |
| ▸ | GSK3B | P49841 | 3/20 | 0.33 |
| ▸ | WNT1 | P04628 | 2/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | LIPE | Q05469 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | WNT3A | P56704 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15538345 | 0.98 | GPR119 (0.35) | GPR119HTR2AHTR2CHTR2BALOX5AP | |
| SCHEMBL15537983 | 0.90 | CYP4F2 (0.38) | GPR119HTR2AHTR2CHTR2BHPGDS | |
| SCHEMBL15539677 | 0.89 | DYRK1A (0.37) | GPR119HPGDSDYRK1AGSK3BWNT1 | |
| SCHEMBL15539766 | 0.89 | WDR5 (0.38) | HTR2AHTR2CHTR2BDYRK1AGSK3B | |
| SCHEMBL15538813 | 0.89 | WDR5 (0.38) | HTR2AHTR2CHTR2BDYRK1AGSK3B | |
| SCHEMBL15538318 | 0.88 | GPR119 (0.36) | GPR119HTR2AHTR2CHTR2BALOX5AP | |
| SCHEMBL15539973 | 0.87 | LIPE (0.37) | GPR119HPGDSDYRK1AGSK3BWNT1 | |
| SCHEMBL15538893 | 0.87 | LIPE (0.37) | GPR119HPGDSDYRK1AGSK3BWNT1 | |
| SCHEMBL15538820 | 0.86 | GPR119 (0.36) | GPR119HTR2AHTR2CHTR2BALOX5AP | |
| SCHEMBL15538132 | 0.86 | GPR119 (0.39) | GPR119HTR2AHTR2CHTR2BHPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2858986-A1 | PIPERIDINE DERIVATIVES FOR GPR119 AGONIST | Chong Kun Dang Pharmaceutical Corp. (KR) | 2015-04-15 | — | — | EP | claimed |
| WO-2013187646-A1 | PIPERIDINE DERIVATIVES FOR GPR119 AGONIST | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2013-12-19 | — | — | WO | claimed |
| EP-2858986-A1 | PIPERIDINE DERIVATIVES FOR GPR119 AGONIST | Chong Kun Dang Pharmaceutical Corp. (KR) | 2015-04-15 | — | — | EP | disclosed |
| WO-2013187646-A1 | PIPERIDINE DERIVATIVES FOR GPR119 AGONIST | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2013-12-19 | — | — | WO | disclosed |