Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 9/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.37 |
| ▸ | WNT1 | P04628 | 2/20 | 0.37 |
| ▸ | PTGES | O14684 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | LIPE | Q05469 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15538813 | 1.00 | WDR5 (0.38) | WDR5DYRK1AWNT1PTGESHTR2A | |
| SCHEMBL15538527 | 0.91 | LIPE (0.39) | DYRK1AWNT1LIPEGSK3B | |
| SCHEMBL15538345 | 0.91 | GPR119 (0.35) | DYRK1AWNT1HTR2AHTR2CHTR2B | |
| SCHEMBL15539246 | 0.89 | DYRK1A (0.39) | DYRK1AWNT1LIPEGSK3B | |
| SCHEMBL15539073 | 0.89 | GPR119 (0.36) | DYRK1AWNT1HTR2AHTR2CHTR2B | |
| SCHEMBL15537678 | 0.88 | WDR5 (0.39) | WDR5DYRK1AWNT1GSK3B | |
| SCHEMBL15538993 | 0.88 | DYRK1A (0.41) | WDR5DYRK1AWNT1PTGESHTR2A | |
| SCHEMBL15539990 | 0.88 | DYRK1A (0.41) | WDR5DYRK1AWNT1PTGESHTR2A | |
| SCHEMBL15539503 | 0.85 | DYRK1A (0.41) | WDR5DYRK1AWNT1HTR2AHTR2C | |
| SCHEMBL15538657 | 0.85 | WNT1 (0.36) | WDR5DYRK1AWNT1HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2858986-A1 | PIPERIDINE DERIVATIVES FOR GPR119 AGONIST | Chong Kun Dang Pharmaceutical Corp. (KR) | 2015-04-15 | — | — | EP | disclosed |
| WO-2013187646-A1 | PIPERIDINE DERIVATIVES FOR GPR119 AGONIST | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2013-12-19 | — | — | WO | disclosed |