Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.50 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16730151 | 1.00 | HPGD (0.55) | HPGDHTR1APLA2G1BATG4BALDH1A1 | |
| SCHEMBL16730186 | 0.87 | HTR1A (0.48) | HPGDHTR1AALDH1A1KDM4EPOLB | |
| SCHEMBL15540224 | 0.87 | HTR1A (0.48) | HPGDHTR1AALDH1A1KDM4EPOLB | |
| SCHEMBL16730223 | 0.87 | HTR1A (0.52) | HPGDHTR1AALDH1A1POLBHTT | |
| SCHEMBL15539841 | 0.87 | HTR1A (0.52) | HPGDHTR1AALDH1A1POLBHTT | |
| SCHEMBL16730173 | 0.85 | HTR1A (0.52) | HTR1APOLBKMT2AADRB2PRMT5 | |
| SCHEMBL15539210 | 0.85 | HTR1A (0.52) | HTR1APOLBKMT2AADRB2PRMT5 | |
| SCHEMBL15540230 | 0.83 | HPGD (0.55) | HPGDHTR1APLA2G1BATG4BALDH1A1 | |
| SCHEMBL16730172 | 0.83 | HPGD (0.55) | HPGDHTR1APLA2G1BATG4BALDH1A1 | |
| SCHEMBL15540454 | 0.82 | P2RX7 (0.59) | HPGDPLA2G1BATG4BALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160318887-A1 | AMIDOPHENOXYPROPANOLAMINES | MEDIZINISCHE UNIVERSITÄT WIEN (AT) | 2016-11-03 | — | — | US | claimed |
| US-20150141437-A1 | AMIDOPHENOXYPROPANOLAMINES | MEDIZINISCHE UNIVERSTÄT WIEN (AT) | 2015-05-21 | — | — | US | claimed |
| EP-2861561-A2 | AMIDOPHENOXYPROPANOLAMINES | Medizinische Universität Wien (AT) | 2015-04-22 | — | — | EP | claimed |
| WO-2013186153-A2 | AMIDOPHENOXYPROPANOLAMINES | MEDIZINISCHE UNIVERSITÄT WIEN (AT) | 2013-12-19 | — | — | WO | claimed |
| US-20160318887-A1 | AMIDOPHENOXYPROPANOLAMINES | MEDIZINISCHE UNIVERSITÄT WIEN (AT) | 2016-11-03 | — | — | US | disclosed |
| US-20150141437-A1 | AMIDOPHENOXYPROPANOLAMINES | MEDIZINISCHE UNIVERSTÄT WIEN (AT) | 2015-05-21 | — | — | US | disclosed |
| EP-2861561-A2 | AMIDOPHENOXYPROPANOLAMINES | Medizinische Universität Wien (AT) | 2015-04-22 | — | — | EP | disclosed |
| WO-2013186153-A2 | AMIDOPHENOXYPROPANOLAMINES | MEDIZINISCHE UNIVERSITÄT WIEN (AT) | 2013-12-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160318887-A1 | AMIDOPHENOXYPROPANOLAMINES | ADH5, HRH3, PNMT | HPGD 1550/4885HTR1A 507/4885PLA2G1B 1127/4885 |
| US-20150141437-A1 | AMIDOPHENOXYPROPANOLAMINES | ADH5, HRH3, PNMT | HPGD 1550/4885HTR1A 507/4885PLA2G1B 1127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.