Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 7/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16730223 | 1.00 | HTR1A (0.52) | HTR1ASGMS2ABCB1POLBEPHX2 | |
| SCHEMBL16730186 | 0.91 | HTR1A (0.48) | HTR1ASGMS2ABCB1POLBLMNA | |
| SCHEMBL15540224 | 0.91 | HTR1A (0.48) | HTR1ASGMS2ABCB1POLBLMNA | |
| SCHEMBL16730207 | 0.90 | ABCB1 (0.52) | HTR1AABCB1POLBEPHX2LMNA | |
| SCHEMBL15539857 | 0.90 | ABCB1 (0.52) | HTR1AABCB1POLBEPHX2LMNA | |
| SCHEMBL15539963 | 0.89 | ABCB1 (0.50) | HTR1AABCB1POLBEPHX2LMNA | |
| SCHEMBL16730224 | 0.89 | ABCB1 (0.50) | HTR1AABCB1POLBEPHX2LMNA | |
| SCHEMBL15539199 | 0.88 | SGMS2 (0.50) | SGMS2ABCB1POLBLMNAMAPT | |
| SCHEMBL15539259 | 0.87 | HPGD (0.55) | HTR1APOLBHPGDKMT2AALDH1A1 | |
| SCHEMBL16730151 | 0.87 | HPGD (0.55) | HTR1APOLBHPGDKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160318887-A1 | AMIDOPHENOXYPROPANOLAMINES | MEDIZINISCHE UNIVERSITÄT WIEN (AT) | 2016-11-03 | — | — | US | claimed |
| US-20150141437-A1 | AMIDOPHENOXYPROPANOLAMINES | MEDIZINISCHE UNIVERSTÄT WIEN (AT) | 2015-05-21 | — | — | US | claimed |
| EP-2861561-A2 | AMIDOPHENOXYPROPANOLAMINES | Medizinische Universität Wien (AT) | 2015-04-22 | — | — | EP | claimed |
| WO-2013186153-A2 | AMIDOPHENOXYPROPANOLAMINES | MEDIZINISCHE UNIVERSITÄT WIEN (AT) | 2013-12-19 | — | — | WO | claimed |
| US-20160318887-A1 | AMIDOPHENOXYPROPANOLAMINES | MEDIZINISCHE UNIVERSITÄT WIEN (AT) | 2016-11-03 | — | — | US | disclosed |
| US-20150141437-A1 | AMIDOPHENOXYPROPANOLAMINES | MEDIZINISCHE UNIVERSTÄT WIEN (AT) | 2015-05-21 | — | — | US | disclosed |
| EP-2861561-A2 | AMIDOPHENOXYPROPANOLAMINES | Medizinische Universität Wien (AT) | 2015-04-22 | — | — | EP | disclosed |
| WO-2013186153-A2 | AMIDOPHENOXYPROPANOLAMINES | MEDIZINISCHE UNIVERSITÄT WIEN (AT) | 2013-12-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160318887-A1 | AMIDOPHENOXYPROPANOLAMINES | ADH5, HRH3, PNMT | HTR1A 507/4885SGMS2 1440/4885ABCB1 1296/4885 |
| US-20150141437-A1 | AMIDOPHENOXYPROPANOLAMINES | ADH5, HRH3, PNMT | HTR1A 507/4885SGMS2 1440/4885ABCB1 1296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.