SCHEMBL1553955

SCHEMBL1553955

NC(CO)c1ccc(Br)cc1

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.44
HTR2A P28223 1/20 0.43
CYP2A6 P11509 1/20 0.38
CYP1A2 P05177 1/20 0.38
ALOX5 P09917 1/20 0.37
MAOA P21397 1/20 0.36
ALOX15 P16050 2/20 0.36
ALDH1A1 P00352 1/20 0.36
MAPK1 P28482 1/20 0.36
OGG1 O15527 1/20 0.35
ANPEP P15144 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1553953 1.00 DPP4 (0.44) DPP4HTR2ACYP2A6CYP1A2ALOX5
SCHEMBL8514591 1.00 DPP4 (0.44) DPP4HTR2ACYP2A6CYP1A2ALOX5
Hydrochloric Acid SCHEMBL17710303 0.98 DPP4 (0.43) DPP4HTR2ACYP2A6CYP1A2ALOX5
Hydrochloric Acid SCHEMBL18765813 0.98 DPP4 (0.43) DPP4HTR2ACYP2A6CYP1A2ALOX5
Hydrochloric Acid SCHEMBL15287423 0.98 DPP4 (0.43) DPP4HTR2ACYP2A6CYP1A2ALOX5
SCHEMBL1444985 0.87 ANPEP (0.41) CYP1A2ALOX15ANPEP
SCHEMBL30200359 0.85 DPP4 (0.36) DPP4HTR2ACYP1A2ALOX5ALDH1A1
SCHEMBL389437 0.82 DPP4 (0.42) DPP4HTR2ACYP2A6CYP1A2ALOX5
SCHEMBL22690052 0.82 DPP4 (0.42) DPP4HTR2ACYP2A6CYP1A2ALOX5
SCHEMBL389436 0.82 DPP4 (0.42) DPP4HTR2ACYP2A6CYP1A2ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116515782-A Amine dehydrogenase mutant and application thereof in chiral amine alcohol compound synthesis 中国科学院天津工业生物技术研究所 2023-08-01 CN claimed
US-20100143322-A1 USE OF INHIBITORS OF N-METHYL TRANSFERASES FOR THE THERAPY OF PARKINSON'S DISEASE PLT PATENT & LICENCE TRADING LTD., C/O THE B-NET (GB) 2010-06-10 US claimed
EP-1917006-A2 USE OF INHIBITORS OF N-METHYL TRANSFERASES FOR THE THERAPY OF PARKINSON'S DISEASE PLT Patent & Licence Trading Ltd. (GB) 2008-05-07 EP claimed
WO-2006136454-A2 USE OF INHIBITORS OF N-METHYL TRANSFERASES FOR THE THERAPY OF PARKINSON'S DISEASE PLT PATENT & LICENCE TRADING LTD. (GB) 2006-12-28 WO claimed
US-20260115296-A1 COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF RAPIDLY ACCELERATED FIBROSARCOMA POLYPEPTIDES UNIV YALE (US) 2026-04-30 US disclosed
US-12552783-B2 Modulators of proteolysis and associated methods of use ARVINAS OPERATIONS, INC. (US) 2026-02-17 US disclosed
US-20260041671-A1 BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE ARVINAS OPERATIONS INC (US) 2026-02-12 US disclosed
US-12539292-B2 BRM targeting compounds and associated methods of use ARVINAS OPERATIONS, INC. (US) 2026-02-03 US disclosed
US-12503452-B2 Antimicrobial compounds and methods CURZA GLOBAL, LLC (US) 2025-12-23 US disclosed
WO-2025125295-A1 THIENO-INDOLE AMIDE DERIVATIVES AS PHGDH INHIBITORS CHIESI FARMACEUTICI S.P.A. (IT) 2025-06-19 WO disclosed
US-20250197387-A1 BCL-XL DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2025-06-19 US disclosed
EP-4537905-A2 BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE Arvinas Operations, Inc. (US) 2025-04-16 EP disclosed
US-6670307-B2 Such as 2-(2,6-difluorophenyl)-4-(4-(2-ethoxypyridin-5-yl) phenyl)oxazoline; for administration to livestock HOECHST SCHERING AGREVO GMBH (DE) 2003-12-30 US disclosed
EP-1087967-B1 1,3-OXAZOLINE AND 1,3-THIAZOLINE DERIVATIVES, METHOD FOR PRODUCING THE SAME AND THEIR USE AS PESTICIDES BAYER CROPSCIENCE GMBH (DE) 2003-10-22 EP disclosed
WO-2003070247-A1 FUSED AZABICYCLIC COMPOUNDS THAT INHIBIT VANILLOID RECEPTOR SUBTYPE 1 (VR1) RECEPTOR ABBOTT LABORATORIES (US) 2003-08-28 WO disclosed
US-20020068828-A1 1,3-oxazoline and 1,3-thiazoline derivatives, their preparation, and their use as pesticides BAYER CROPSCIENCE AG (DE) 2002-06-06 US disclosed
CN-1305476-A 1,3-oxazoline and 1,3-thiazoline derivatives, method for producing the same and their use as pesticides AVENTIS CORP SCIENCE GMBH (DE) 2001-07-25 CN disclosed
US-6265350-B1 CONTROLLING HARMFUL FUNGI, INSECTS, ACARINA, MOLLUSKS AND NEMATODES HOECHST SCHERING AGREVO GMBH (DE) 2001-07-24 US disclosed
EP-1087967-A1 1,3-OXAZOLINE AND 1,3-THIAZOLINE DERIVATIVES, METHOD FOR PRODUCING THE SAME AND THEIR USE AS PESTICIDES Aventis CropScience GmbH (DE) 2001-04-04 EP disclosed
WO-1999065901-A1 1,3-OXAZOLINE AND 1,3-THIAZOLINE DERIVATIVES, METHOD FOR PRODUCING THE SAME AND THEIR USE AS PESTICIDES AVENTIS CROPSCIENCE GMBH (DE) 1999-12-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12539292-B2 BRM targeting compounds and associated methods of use ADRM1, SUMO2, BAZ1A DPP4 4653/4885HTR2A 2680/4885CYP2A6 4194/4885
US-20020068828-A1 1,3-oxazoline and 1,3-thiazoline derivatives, their preparation, and their use as pesticides MT-CO1, OXA1L, MT-CO3 DPP4 710/4885HTR2A 3520/4885CYP2A6 775/4885
US-20250197387-A1 BCL-XL DEGRADERS AND USES THEREOF XIAP, BCL2L1, BCL2L10 DPP4 3374/4885HTR2A 3995/4885CYP2A6 4274/4885
US-20260041671-A1 BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE ADRM1, VHL, BAZ1A DPP4 4616/4885HTR2A 2742/4885CYP2A6 4179/4885
US-12552783-B2 Modulators of proteolysis and associated methods of use CRBN, ADRM1, MDM2 DPP4 4191/4885HTR2A 3158/4885CYP2A6 4321/4885
US-20260115296-A1 COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF RAPIDLY ACCELERATED FIBROSARCOMA POLYPEPTIDES CRBN, VHL, ADRM1 DPP4 4643/4885HTR2A 4010/4885CYP2A6 4009/4885
US-12503452-B2 Antimicrobial compounds and methods MPO, NISCH, RPN2 DPP4 130/4885HTR2A 4712/4885CYP2A6 2616/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.