Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | DPP4 | P27487 | 5/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14655522 | 0.85 | EPHX1 (0.52) | EPHX1KCNH2DPP4DPP7 | |
| SCHEMBL1553960 | 0.81 | SIGMAR1 (0.47) | EPHX1HRH3KCNH2KDM4E | |
| SCHEMBL1554795 | 0.80 | EPHX2 (0.49) | EPHX1KDM4E | |
| SCHEMBL6187047 | 0.79 | EPHX1 (0.46) | EPHX1KCNH2CA2DPP4DPP7 | |
| SCHEMBL1555148 | 0.75 | EPHX1 (0.39) | EPHX1KDM4EDPP4DPP7 | |
| SCHEMBL19293305 | 0.70 | KDM4E (0.48) | EPHX1KDM4ECA12CA1CA2 | |
| SCHEMBL30771313 | 0.70 | KDM4E (0.51) | EPHX1KDM4ECA12CA1CA2 | |
| SCHEMBL1555261 | 0.70 | SIGMAR1 (0.35) | EPHX1CYP2D6KDM4ECA2 | |
| SCHEMBL23716166 | 0.70 | HRH3 (0.38) | HRH3CYP2D6KCNH2KDM4E | |
| SCHEMBL931217 | 0.69 | EPHX1 (0.60) | EPHX1CA12CA1CA2MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011000945-A2 | AMINOALKAMIDES FOR USE IN THE TREATMENT OF INFLAMMATORY, DEGENERATIVE OR DEMYELINATING DISEASES OF THE CNS | NENSIUS RESEARCH A/S (DK) | 2011-01-06 | — | — | WO | disclosed |