Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL944062 | 0.80 | EPHX1 (0.46) | EPHX1KDM4E | |
| SCHEMBL14655522 | 0.79 | EPHX1 (0.52) | EPHX1TSHR | |
| SCHEMBL1554587 | 0.75 | EPHX2 (0.41) | EPHX2HSD11B1CASP6BLMALDH1A1 | |
| SCHEMBL1553960 | 0.75 | SIGMAR1 (0.47) | EPHX1POLBKDM4EALDH1A1SIGMAR1 | |
| SCHEMBL6187047 | 0.73 | EPHX1 (0.46) | EPHX1SIGMAR1 | |
| SCHEMBL931735 | 0.73 | BLM (0.41) | EPHX2POLBKDM4EBLMTSHR | |
| SCHEMBL1555148 | 0.72 | EPHX1 (0.39) | EPHX1POLBKDM4EPKMTSHR | |
| SCHEMBL975191 | 0.70 | KDM4E (0.64) | EPHX2EPHX1KDM4ECASP6ALDH1A1 | |
| SCHEMBL13453030 | 0.69 | EPHX2 (0.54) | EPHX2POLBKDM4ETSHRALDH1A1 | |
| SCHEMBL12518918 | 0.69 | ALDH1A1 (0.70) | EPHX2HSD11B1TSHRALDH1A1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011000945-A9 | AMINOALKAMIDES FOR USE IN THE TREATMENT OF INFLAMMATORY, DEGENERATIVE OR DEMYELINATING DISEASES OF THE CNS | NENSIUS RESEARCH A/S (DK) | 2011-04-07 | — | — | WO | disclosed |