Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMKLR1 | Q99788 | 6/20 | 0.48 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3821755 | 0.92 | AGTR2 (0.45) | CMKLR1LTB4R2AGTR2 | |
| SCHEMBL789857 | 0.87 | ABCB11 (0.36) | CMKLR1LTB4R2AGTR2 | |
| SCHEMBL844427 | 0.84 | ABCB11 (0.38) | LTB4R2AGTR2 | |
| SCHEMBL5746358 | 0.78 | PPARG (0.34) | LTB4R2AGTR2 | |
| SCHEMBL3638790 | 0.77 | AGTR1 (0.39) | LTB4R2AGTR2 | |
| SCHEMBL9291479 | 0.76 | PARP1 (0.35) | LTB4R2AGTR2 | |
| SCHEMBL8836872 | 0.76 | BRS3 (0.33) | LTB4R2AGTR2 | |
| SCHEMBL4119807 | 0.75 | DHODH (0.44) | CMKLR1 | |
| Azilsartan SCHEMBL167538 | 0.73 | AGTR2 (0.72) | LTB4R2AGTR2 | |
| Azilsartan SCHEMBL29687472 | 0.73 | AGTR2 (0.72) | LTB4R2AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013186792-A2 | PROCESS FOR THE PREPARATION OF (5-METHYL-2-OXO-L,3-DIOXOI-4-VL)METHVL 2- ETHOXV-L-{[2'-(5-OXO-4,5-DIHVDRO-L,2,4-OXADIAZOL-3-VL)BIPHENYI-4-VL]METHYL}- LH-BENZIMIDAZOLE-7-CARBOXYIATE AND ITS SALTS | MSN LABORATORIES LIMITED (IN) | 2013-12-19 | — | — | WO | disclosed |