SCHEMBL15540434

SCHEMBL15540434

C=CSC=C.Cc1cc(CCC(=O)O)cc(CC(C)C)c1O.Cc1cc(CCC(=O)O)cc(CC(C)C)c1O

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
THRA P10827 5/20 0.40
THRB P10828 5/20 0.40
NPSR1 Q6W5P4 1/20 0.38
FFAR4 Q5NUL3 7/20 0.37
S1PR1 P21453 3/20 0.37
S1PR3 Q99500 1/20 0.35
FFAR1 O14842 2/20 0.35
TP53 P04637 1/20 0.35
MDM2 Q00987 1/20 0.35
BCL2L1 Q07817 1/20 0.34
MCL1 Q07820 1/20 0.34
ALOX5 P09917 1/20 0.34
NFKB1 P19838 1/20 0.34
NFKB2 Q00653 1/20 0.34
RELA Q04206 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28666259 0.90 THRA (0.47) THRATHRBNPSR1FFAR4S1PR1
SCHEMBL5335738 0.83 THRA (0.38) THRATHRBNPSR1FFAR4S1PR1
SCHEMBL17260612 0.81 THRA (0.49) THRATHRBNPSR1FFAR4TP53
Triethylene Glycol SCHEMBL9940408 0.80 THRA (0.43) THRATHRBNPSR1FFAR4S1PR1
SCHEMBL31489832 0.78 GAA (0.46) THRATHRBNPSR1
SCHEMBL2947656 0.78 GAA (0.46) THRATHRBNPSR1
SCHEMBL26229210 0.76 ALOX5 (0.43) THRATHRBS1PR1S1PR3ALOX5
SCHEMBL2023496 0.74 THRA (0.41) THRATHRBNPSR1FFAR4FFAR1
SCHEMBL17260589 0.74 THRA (0.46) THRATHRBNPSR1FFAR4TP53
SCHEMBL3580792 0.73 NPSR1 (0.55) THRATHRBNPSR1FFAR4S1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3137540-A1 STABILIZING COMPOSITIONS FOR STABILIZING MATERIALS AGAINST ULTRAVIOLET LIGHT AND THERMAL DEGRADATION Cytec Industries Inc. (US) 2017-03-08 EP claimed
WO-2015168389-A1 STABILIZING COMPOSITIONS FOR STABILIZING MATERIALS AGAINST ULTRAVIOLET LIGHT AND THERMAL DEGRADATION CYTEC INDUSTRIES INC. (US) 2015-11-05 WO claimed
EP-2864310-A1 STABILIZER COMPOSITIONS CONTAINING SUBSTITUTED CHROMAN COMPOUNDS AND METHODS OF USE Cytec Technology Corp. (US) 2015-04-29 EP claimed
WO-2013188490-A1 STABILIZER COMPOSITIONS CONTAINING SUBSTITUTED CHROMAN COMPOUNDS AND METHODS OF USE CYTEC TECHNOLOGY CORP. (US) 2013-12-19 WO claimed
EP-3137540-A1 STABILIZING COMPOSITIONS FOR STABILIZING MATERIALS AGAINST ULTRAVIOLET LIGHT AND THERMAL DEGRADATION Cytec Industries Inc. (US) 2017-03-08 EP disclosed
WO-2015168389-A1 STABILIZING COMPOSITIONS FOR STABILIZING MATERIALS AGAINST ULTRAVIOLET LIGHT AND THERMAL DEGRADATION CYTEC INDUSTRIES INC. (US) 2015-11-05 WO disclosed
EP-2864310-A1 STABILIZER COMPOSITIONS CONTAINING SUBSTITUTED CHROMAN COMPOUNDS AND METHODS OF USE Cytec Technology Corp. (US) 2015-04-29 EP disclosed
WO-2013188490-A1 STABILIZER COMPOSITIONS CONTAINING SUBSTITUTED CHROMAN COMPOUNDS AND METHODS OF USE CYTEC TECHNOLOGY CORP. (US) 2013-12-19 WO disclosed