SCHEMBL28666259

SCHEMBL28666259

Cc1cc(CCC(=O)O)cc(CC(C)C)c1O

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
THRA P10827 5/20 0.47
THRB P10828 5/20 0.47
NPSR1 Q6W5P4 1/20 0.46
S1PR1 P21453 2/20 0.42
FFAR4 Q5NUL3 6/20 0.40
S1PR3 Q99500 1/20 0.40
SHBG P04278 1/20 0.40
FFAR1 O14842 1/20 0.40
TP53 P04637 1/20 0.39
MDM2 Q00987 1/20 0.39
ALOX5 P09917 1/20 0.39
NFKB1 P19838 1/20 0.39
NFKB2 Q00653 1/20 0.39
RELA Q04206 1/20 0.39
GABRA1 P14867 1/20 0.39
GABRB2 P47870 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17260612 0.91 THRA (0.49) THRATHRBNPSR1FFAR4TP53
SCHEMBL15540434 0.90 THRA (0.40) THRATHRBNPSR1S1PR1FFAR4
Triethylene Glycol SCHEMBL9940408 0.89 THRA (0.43) THRATHRBNPSR1S1PR1FFAR4
SCHEMBL26229210 0.84 ALOX5 (0.43) THRATHRBS1PR1S1PR3SHBG
SCHEMBL17260589 0.82 THRA (0.46) THRATHRBNPSR1FFAR4TP53
SCHEMBL3580792 0.82 NPSR1 (0.55) THRATHRBNPSR1S1PR1FFAR4
SCHEMBL9940405 0.81 ALOX5 (0.41) THRATHRBS1PR1S1PR3SHBG
SCHEMBL10015716 0.81 ALOX5 (0.41) THRATHRBSHBGALOX5NFKB1
SCHEMBL23387416 0.80 GABRA1 (0.53) SHBGGABRA1GABRB2
SCHEMBL38650833 0.80 GABRA1 (0.53) SHBGGABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113671068-A Method for analyzing environmental pollutant targeting exposure component in blood plasma and application thereof 暨南大学 2021-11-19 CN disclosed