Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | ATM | Q13315 | 3/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15554204 | 0.89 | ALDH1A1 (0.42) | RAB9AL3MBTL1NPC1ATMESR1 | |
| SCHEMBL15554828 | 0.87 | RAB9A (0.50) | RAB9AL3MBTL1NPC1ATMESR1 | |
| SCHEMBL15560269 | 0.86 | KCNN4 (0.40) | RAB9ANPC1ATMMAPTSMN1; SMN2 | |
| SCHEMBL15554672 | 0.85 | RAB9A (0.48) | RAB9AL3MBTL1NPC1ATMESR1 | |
| SCHEMBL15543200 | 0.84 | RAB9A (0.55) | RAB9AL3MBTL1NPC1ATMESR1 | |
| SCHEMBL15555334 | 0.82 | LMNA (0.41) | RAB9AL3MBTL1NPC1ATMESR1 | |
| SCHEMBL15555237 | 0.82 | LMNA (0.44) | RAB9AL3MBTL1NPC1ATMESR1 | |
| SCHEMBL15555127 | 0.80 | L3MBTL1 (0.47) | RAB9AL3MBTL1NPC1ESR1MAPT | |
| SCHEMBL15560287 | 0.80 | LMNA (0.46) | RAB9AL3MBTL1NPC1ATMESR1 | |
| SCHEMBL15560043 | 0.79 | RAB9A (0.57) | RAB9AL3MBTL1NPC1ATMESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014002109-A1 | SUBSTITUTED TETRAZOLE COMPOUNDS AND PROCESS THEREOF | RALLIS INDIA LIMITED (IN) | 2014-01-03 | — | — | WO | disclosed |