Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 7/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15554391 | 0.88 | RAB9A (0.40) | SMN1; SMN2LMNANPC1RAB9AALDH1A1 | |
| SCHEMBL15555060 | 0.87 | TRPM8 (0.43) | SMN1; SMN2LMNANPC1RAB9AALDH1A1 | |
| SCHEMBL15543006 | 0.86 | RAB9A (0.49) | ATMSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL15553430 | 0.86 | ATM (0.40) | KCNN4ATMSMN1; SMN2LMNANPC1 | |
| SCHEMBL15555466 | 0.86 | PIM1 (0.41) | KCNN4ATMSMN1; SMN2LMNANPC1 | |
| SCHEMBL15556004 | 0.86 | ATM (0.40) | KCNN4ATMSMN1; SMN2LMNANPC1 | |
| SCHEMBL15555317 | 0.85 | ATM (0.39) | KCNN4ATMSMN1; SMN2LMNANPC1 | |
| SCHEMBL15560549 | 0.83 | NPC1 (0.45) | KCNN4SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL15542982 | 0.83 | LMNA (0.41) | SMN1; SMN2LMNANPC1RAB9AALDH1A1 | |
| SCHEMBL15554204 | 0.82 | ALDH1A1 (0.42) | ATMSMN1; SMN2NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014002109-A1 | SUBSTITUTED TETRAZOLE COMPOUNDS AND PROCESS THEREOF | RALLIS INDIA LIMITED (IN) | 2014-01-03 | — | — | WO | disclosed |