Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 9/20 | 0.37 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 4/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.32 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.32 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL709768 | 0.76 | CES1 (0.43) | MAPK14KCNH3IDH1HRH4 | |
| SCHEMBL1554486 | 0.76 | MAPK14 (0.36) | MAPK14KCNH3USP2CYP1A2CYP3A4 | |
| SCHEMBL1555485 | 0.76 | MAPK14 (0.36) | MAPK14KCNH3USP2CYP1A2CYP3A4 | |
| SCHEMBL5788690 | 0.70 | LTA4H (0.49) | USP2CYP1A2CYP2C19GRM1 | |
| SCHEMBL1554350 | 0.67 | RAB9A (0.50) | MAPK14KCNH3IDH1 | |
| SCHEMBL28748558 | 0.66 | TRPV1 (0.33) | MAPK14USP2CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL27516993 | 0.66 | TRPV1 (0.33) | MAPK14USP2CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL1554351 | 0.65 | IDH1 (0.43) | MAPK14KCNH3IDH1HRH4MAPK13 | |
| SCHEMBL8094065 | 0.64 | LMNA (0.40) | CYP1A2CYP2C19 | |
| SCHEMBL8094061 | 0.64 | LMNA (0.40) | CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2486031-A2 | Phenylpyri(mi)dinylpyrazoles and their use as fungicides | Bayer CropScience AG (DE) | 2012-08-15 | — | — | EP | disclosed |
| WO-2011042389-A2 | PHENYLPYRI(MI)DINYLAZOLES | BAYER CROPSCIENCE AG (DE) | 2011-04-14 | — | — | WO | disclosed |