SCHEMBL15545301

SCHEMBL15545301

O=C1c2c(O)cc(O)cc2OC(c2cc(O)cc(O)c2)C1O

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SOST Q9BQB4 2/20 0.83
SYNJ2 O15056 1/20 0.83
APP P05067 1/20 0.83
MAPT P10636 4/20 0.74
CYP3A4 P08684 4/20 0.74
ALOX15 P16050 4/20 0.74
MEN1 O00255 3/20 0.74
KMT2A Q03164 3/20 0.74
HSD17B10 Q99714 3/20 0.74
RECQL P46063 2/20 0.74
POLB P06746 2/20 0.74
KDM4E B2RXH2 2/20 0.74
GAA P10253 2/20 0.74
ALOX12 P18054 2/20 0.74
HIF1A Q16665 2/20 0.74
CYP1A2 P05177 1/20 0.74
NFKB1 P19838 1/20 0.74
MAPK1 P28482 1/20 0.74
XDH P47989 1/20 0.73
FASN P49327 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ampelopsin SCHEMBL22750858 0.91 SYNJ2 (1.00) SOSTSYNJ2APPMAPTCYP3A4
Ampelopsin SCHEMBL134532 0.91 SYNJ2 (1.00) SOSTSYNJ2APPMAPTCYP3A4
Ampelopsin SCHEMBL29462401 0.91 SYNJ2 (1.00) SOSTSYNJ2APPMAPTCYP3A4
Ampelopsin SCHEMBL134531 0.91 SYNJ2 (1.00) SOSTSYNJ2APPMAPTCYP3A4
Ampelopsin SCHEMBL29138729 0.91 SYNJ2 (1.00) SOSTSYNJ2APPMAPTCYP3A4
Ampelopsin SCHEMBL29362330 0.91 SYNJ2 (1.00) SOSTSYNJ2APPMAPTCYP3A4
Ampelopsin SCHEMBL723736 0.91 SYNJ2 (1.00) SOSTSYNJ2APPMAPTCYP3A4
Ampelopsin SCHEMBL544092 0.90 SYNJ2 (0.97) SOSTSYNJ2APPMAPTCYP3A4
Dihydrokaempferol SCHEMBL39319 0.88 CYP3A4 (0.80) SOSTSYNJ2APPMAPTCYP3A4
Dihydrokaempferol SCHEMBL13354175 0.88 CYP3A4 (0.80) SOSTSYNJ2APPMAPTCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111718318-B Method for separating flavone monomer in spina gleditsiae based on countercurrent chromatography 山东省分析测试中心 2022-04-22 CN claimed
CN-111718318-A Method for separating flavone monomer in spina gleditsiae based on countercurrent chromatography 山东省分析测试中心 2020-09-29 CN claimed
CN-114957362-B Method for separating anti-inflammatory active ingredients of coreopsis tinctoria 中国科学院西北高原生物研究所 2023-11-10 CN disclosed
CN-111718318-B Method for separating flavone monomer in spina gleditsiae based on countercurrent chromatography 山东省分析测试中心 2022-04-22 CN disclosed
CN-111718318-A Method for separating flavone monomer in spina gleditsiae based on countercurrent chromatography 山东省分析测试中心 2020-09-29 CN disclosed
CN-111450139-A Eutectic solvent and method for preparing spina gleditsiae total flavonoids by using same 山东省分析测试中心 2020-07-28 CN disclosed
CN-111450139-A Eutectic solvent and method for preparing spina gleditsiae total flavonoids by using same 山东省分析测试中心 2020-07-28 CN disclosed
CN-109172640-A Application of the flavones ingredient in the drug for preparing anti-oral cavity bacterial diseases in paper mulberry 中国科学院昆明植物研究所 2019-01-11 CN disclosed
CN-109172640-A Application of the flavones ingredient in the drug for preparing anti-oral cavity bacterial diseases in paper mulberry 中国科学院昆明植物研究所 2019-01-11 CN disclosed
WO-2014007853-A1 DIHYDROMYRICETIN FOR THE TREATMENT OF DISEASES AND DISORDERS OF THE GLUTAMATERGIC SYSTEM THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2014-01-09 WO disclosed