Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYNJ2 | O15056 | 3/20 | 1.00 |
| ▸ | SOST | Q9BQB4 | 2/20 | 1.00 |
| ▸ | APP | P05067 | 1/20 | 1.00 |
| ▸ | RECQL | P46063 | 4/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.75 |
| ▸ | MAPT | P10636 | 2/20 | 0.75 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.75 |
| ▸ | MEN1 | O00255 | 1/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.75 |
| ▸ | POLB | P06746 | 1/20 | 0.75 |
| ▸ | GAA | P10253 | 1/20 | 0.75 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.75 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.75 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.75 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.75 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.75 |
| ▸ | XDH | P47989 | 2/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ampelopsin SCHEMBL134531 | 1.00 | SYNJ2 (1.00) | SYNJ2SOSTAPPRECQLKDM4E | |
| Ampelopsin SCHEMBL22750858 | 1.00 | SYNJ2 (1.00) | SYNJ2SOSTAPPRECQLKDM4E | |
| Ampelopsin SCHEMBL29462401 | 1.00 | SYNJ2 (1.00) | SYNJ2SOSTAPPRECQLKDM4E | |
| Ampelopsin SCHEMBL29138729 | 1.00 | SYNJ2 (1.00) | SYNJ2SOSTAPPRECQLKDM4E | |
| Ampelopsin SCHEMBL29362330 | 1.00 | SYNJ2 (1.00) | SYNJ2SOSTAPPRECQLKDM4E | |
| Ampelopsin SCHEMBL134532 | 1.00 | SYNJ2 (1.00) | SYNJ2SOSTAPPRECQLKDM4E | |
| Ampelopsin SCHEMBL544092 | 0.99 | SYNJ2 (0.97) | SYNJ2SOSTAPPRECQLKDM4E | |
| Ampelopsin SCHEMBL28158121 | 0.93 | SOST (0.87) | SYNJ2SOSTAPPRECQLKDM4E | |
| SCHEMBL15545301 | 0.91 | SOST (0.83) | SYNJ2SOSTAPPRECQLKDM4E | |
| SCHEMBL21587452 | 0.91 | SYNJ2 (0.82) | SYNJ2SOSTAPPRECQLKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 303 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120202190-A | Isoquinoline derivatives as protein degrading agents, E7 degrading agents, antiviral agents, tumor therapeutic agents and immunosuppressants | RDP制药股份公司 | 2025-06-24 | — | — | CN | claimed |
| EP-4548977-A2 | NOVEL ISOQUINOLINES AS PROTEIN DEGRADERS, E7 DEGRADERS, ANTIVIRALS, TUMOR THERAPEUTICS AND IMMUNE SUPPRESSIVES | RDP Pharma AG (CH) | 2025-05-07 | — | — | EP | claimed |
| US-20240315965-A1 | COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS | Natural Extraction Systems, LLC (US) | 2024-09-26 | — | — | US | claimed |
| EP-4322949-A1 | ISOQUINOLINE DERIVATIVES FOR USE AS ANTIVIRAL AND ANTITUMOUR AGENTS | RDP Pharma AG (CH) | 2024-02-21 | — | — | EP | claimed |
| WO-2022219157-A1 | ISOQUINOLINE DERIVATIVES FOR USE AS ANTIVIRAL AND ANTITUMOUR AGENTS | VALDOSPAN GMBH (AT) | 2022-10-20 | — | — | WO | claimed |
| WO-2022182527-A1 | COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS | Natural Extraction Systems, LLC (US) | 2022-09-01 | — | — | WO | claimed |
| WO-2022122968-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF COVID-19 | DOMPE' FARMACEUTICI SPA (IT) | 2022-06-16 | — | — | WO | claimed |
| WO-2021042001-A1 | COMPOSITIONS AND METHODS RELATED TO DISSOLVED OXIDES | Natural Extraction Systems, LLC (US) | 2021-03-04 | — | — | WO | claimed |
| CN-105949169-A | Ampeloptin medicine composition and application thereof to biological medicine | 淄博夸克医药技术有限公司 | 2016-09-21 | — | — | CN | claimed |
| US-9139551-B2 | Preparation of a new class of water-soluble ammonium 2,3-dihydroxy-5-((2R,3R)-3,5,7-trihydroxy-4-oxochroman-2-yl) phenolates and their biological activity of alcohol elimination | JIANG XIANXING (CN) | 2015-09-22 | — | — | US | claimed |
| US-20150203465-A1 | Preparation Of A New Class Of Water-Soluble Ammonium 2,3-Dihydroxy-5-((2R,3R)-3,5,7-Trihydroxy-4-Oxochroman-2-Yl) Phenolates And Their Biological Activity Of Alcohol Elimination | JIANG XIANXING (CN) | 2015-07-23 | — | — | US | claimed |
| CN-104721181-A | Application of dihydromyricetin for preparation of preparation for promoting sleep and improving sleep quality | LUO GUANDI | 2015-06-24 | — | — | CN | claimed |
| CN-102772398-A | Application of dihydromyricetin in preparation of drug preventing and treating influenza | GUIZHOU INST BIOLOGY | 2012-11-14 | — | — | CN | claimed |
| CN-101336978-A | Extraction method of total flavone of Hovenia dulcisThunb | UNIV NORTHWEST SCI TECH AGRI (CN) | 2009-01-07 | — | — | CN | claimed |
| CN-101336987-A | Preparation method of total flavone of Hovenia dulcisThunb | UNIV NORTHWEST SCI TECH AGRI (CN) | 2009-01-07 | — | — | CN | claimed |
| CN-122081128-A | Lactobacillus rhamnosus and application thereof | — | 2026-05-26 | — | — | CN | disclosed |
| CN-122005956-A | Low-viscosity easy-absorption human body lubricant and preparation method thereof | 优护优家健康科技(江苏)有限公司 | 2026-05-12 | — | — | CN | disclosed |
| US-4933399-A | COATING INSIDE OF VESSEL WITH A CATIONIC DYE, DRYING, COATING WITH AN ANIONIC OR AMPHOTERIC POLYMER OR A HYDROXYL-CONTAINING COMPOUND IN A SOLVENT | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1990-06-12 | — | — | US | disclosed |
| CN-1035118-A | A kind of method that forms polymer-scale that stops | SHINETSU CHEMICAL CO (JP) | 1989-08-30 | — | — | CN | disclosed |
| EP-0320227-A2 | Method of preventing polymer-scale formation | Shin-Etsu Chemical Co., Ltd. (JP) | 1989-06-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150203465-A1 | Preparation Of A New Class Of Water-Soluble Ammonium 2,3-Dihydroxy-5-((2R,3R)-3,5,7-Trihydroxy-4-Oxochroman-2-Yl) Phenolates And Their Biological Activity Of Alcohol Elimination | DBH, ADH1A, ADH1C | SYNJ2 3717/4885SOST 4046/4885APP 4016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.