Ampelopsin

Ampelopsin

SCHEMBL134532

O=C1c2c(O)cc(O)cc2OC(c2cc(O)c(O)c(O)c2)C1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SYNJ2 O15056 3/20 1.00
SOST Q9BQB4 2/20 1.00
APP P05067 1/20 1.00
RECQL P46063 4/20 0.75
KDM4E B2RXH2 2/20 0.75
MAPT P10636 2/20 0.75
ALOX15 P16050 2/20 0.75
HSD17B10 Q99714 2/20 0.75
MEN1 O00255 1/20 0.75
KMT2A Q03164 1/20 0.75
POLB P06746 1/20 0.75
GAA P10253 1/20 0.75
CYP1A2 P05177 1/20 0.75
CYP3A4 P08684 1/20 0.75
ALOX12 P18054 1/20 0.75
NFKB1 P19838 1/20 0.75
MAPK1 P28482 1/20 0.75
HIF1A Q16665 1/20 0.75
XDH P47989 2/20 0.74
TDP1 Q9NUW8 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ampelopsin SCHEMBL134531 1.00 SYNJ2 (1.00) SYNJ2SOSTAPPRECQLKDM4E
Ampelopsin SCHEMBL22750858 1.00 SYNJ2 (1.00) SYNJ2SOSTAPPRECQLKDM4E
Ampelopsin SCHEMBL29462401 1.00 SYNJ2 (1.00) SYNJ2SOSTAPPRECQLKDM4E
Ampelopsin SCHEMBL29138729 1.00 SYNJ2 (1.00) SYNJ2SOSTAPPRECQLKDM4E
Ampelopsin SCHEMBL29362330 1.00 SYNJ2 (1.00) SYNJ2SOSTAPPRECQLKDM4E
Ampelopsin SCHEMBL723736 1.00 SYNJ2 (1.00) SYNJ2SOSTAPPRECQLKDM4E
Ampelopsin SCHEMBL544092 0.99 SYNJ2 (0.97) SYNJ2SOSTAPPRECQLKDM4E
Ampelopsin SCHEMBL28158121 0.93 SOST (0.87) SYNJ2SOSTAPPRECQLKDM4E
SCHEMBL15545301 0.91 SOST (0.83) SYNJ2SOSTAPPRECQLKDM4E
SCHEMBL21587452 0.91 SYNJ2 (0.82) SYNJ2SOSTAPPRECQLKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5451 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122075772-A Hydrogel with wet adhesion and antioxidation functions as well as preparation method and application thereof 2026-05-26 CN claimed
CN-122074654-A Microcapsule type composition for reducing blood sugar and preparation method and application thereof 2026-05-26 CN claimed
CN-122075596-A Plant extract rich in functional flavone compound, and preparation method and application thereof 2026-05-26 CN claimed
CN-122056874-A Use of DVM nanoparticles for the preparation of a product for the treatment and/or prevention of alcoholic liver disease 昆明理工大学 2026-05-19 CN claimed
CN-122036670-A Method for separating and purifying dihydromyricetin from strawberry tea 江苏长远生物医药科技有限公司 2026-05-15 CN claimed
US-20260130371-A1 COMPOSITION FOR PROMOTING EARLY HARVEST OF RICE SEEDS, PREPARATION METHOD AND APPLICATION THEREOF AGRO-BIOLOGICAL GENE RESEARCH CENTER OF GAAS (CN) 2026-05-14 US claimed
CN-122005956-A Low-viscosity easy-absorption human body lubricant and preparation method thereof 优护优家健康科技(江苏)有限公司 2026-05-12 CN claimed
US-12617764-B2 Dihydromyricetin extraction and purification process Dr Kang International Limited (CN) 2026-05-05 US claimed
EP-4363043-B1 COMPOSITIONS FOR USE IN METHODS FOR INCREASING CANCER CELL SENSITIVITY TO ALTERNATING ELECTRIC FIELDS NOVOCURE GMBH (CH) 2026-04-22 EP claimed
US-12594421-B2 Compositions and methods for increasing cancer cell sensitivity to alternating electric fields NOVOCURE GMBH (CH) 2026-04-07 US claimed
US-6555734-B2 Modified dihydroflavonol 4-reductase (DFR) nucleic acids;encoding the modified DFR characterized by its ability to reduce dihydrokaempferol preferentially and increase the content of pelargonidin-based pigments KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2003-04-29 US claimed
CN-1399916-A Application of dihydromyricetin in preparation of food, cosmetics or medicine ZHANG YOUSHENG (CN) 2003-03-05 CN claimed
CN-1393443-A Process for preparing dihydromyricetin from porcelain ampelopsis ZHANG YOUSHENG (CN) 2003-01-29 CN claimed
US-6465630-B1 ISOLATED NUCLEIC ACID ENCODING A DIHYDROFLAVANOL 4-REDUCTASE THAT SELECTIVELY CATALYZES THE REDUCTION OF DIHYDROKAEMPFEROL TO LEUCOPELARGONIDIN IN THE PRESENCE OF DIHYDROQUERCETIN AND DIHYDROMYRICETIN COMPRISING A NUCLEIC ACID SEQUENCE, KOREA KUMHO PETROCHEMICAL CO. LTD. (KR) 2002-10-15 US claimed
CN-1288747-A Pharmaceutical composition containing dihydromyricetin SONG XINRONG (CN) 2001-03-28 CN claimed
EP-0316797-B1 Plants with a modified flowering colour and genetic engineering method for their production MAX PLANCK GESELLSCHAFT (DE) 1993-10-20 EP claimed
EP-0290442-A4 PHARMACOLOGICALLY ACTIVE COMPOUNDS AND MIXTURES THEREOF, ORGANIC COMPOSITIONS AND METAL SALTS. CHEMEX PHARMACEUTICALS INC (US) 1990-07-03 EP claimed
EP-0290442-A1 PHARMACOLOGICALLY ACTIVE COMPOUNDS AND MIXTURES THEREOF, ORGANIC COMPOSITIONS AND METAL SALTS CHEMEX PHARMACEUTICALS, INC. (US) 1988-11-17 EP claimed
WO-1988003805-A1 PHARMACOLOGICALLY ACTIVE COMPOUNDS AND MIXTURES THEREOF, ORGANIC COMPOSITIONS AND METAL SALTS CHEMEX PHARMACEUTICALS, INC. (US) 1988-06-02 WO claimed
WO-1987006833-A1 MODIFICATION OF PLANT EXTRACTS FROM ZYGOPHYLLACEAE CHEMEX PHARMACEUTICALS, INC. (US) 1987-11-19 WO claimed