Ampelopsin

Ampelopsin

SCHEMBL544092

O=C1c2c(O)cc(O)cc2O[C@@H](c2cc(O)c(O)c(O)c2)[C@@H]1O.[NaH]

nearest known ligand 0.97

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SYNJ2 O15056 3/20 0.97
SOST Q9BQB4 2/20 0.97
APP P05067 1/20 0.97
RECQL P46063 4/20 0.73
KDM4E B2RXH2 2/20 0.73
MAPT P10636 2/20 0.73
ALOX15 P16050 2/20 0.73
HSD17B10 Q99714 2/20 0.73
MEN1 O00255 1/20 0.73
KMT2A Q03164 1/20 0.73
POLB P06746 1/20 0.73
GAA P10253 1/20 0.73
CYP1A2 P05177 1/20 0.73
CYP3A4 P08684 1/20 0.73
ALOX12 P18054 1/20 0.73
NFKB1 P19838 1/20 0.73
MAPK1 P28482 1/20 0.73
HIF1A Q16665 1/20 0.73
XDH P47989 2/20 0.72
TDP1 Q9NUW8 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ampelopsin SCHEMBL134531 0.99 SYNJ2 (1.00) SYNJ2SOSTAPPRECQLKDM4E
Ampelopsin SCHEMBL29138729 0.99 SYNJ2 (1.00) SYNJ2SOSTAPPRECQLKDM4E
Ampelopsin SCHEMBL29362330 0.99 SYNJ2 (1.00) SYNJ2SOSTAPPRECQLKDM4E
Ampelopsin SCHEMBL29462401 0.99 SYNJ2 (1.00) SYNJ2SOSTAPPRECQLKDM4E
Ampelopsin SCHEMBL723736 0.99 SYNJ2 (1.00) SYNJ2SOSTAPPRECQLKDM4E
Ampelopsin SCHEMBL134532 0.99 SYNJ2 (1.00) SYNJ2SOSTAPPRECQLKDM4E
Ampelopsin SCHEMBL22750858 0.99 SYNJ2 (1.00) SYNJ2SOSTAPPRECQLKDM4E
Ampelopsin SCHEMBL28158121 0.92 SOST (0.87) SYNJ2SOSTAPPRECQLKDM4E
SCHEMBL15545301 0.90 SOST (0.83) SYNJ2SOSTAPPRECQLKDM4E
SCHEMBL21587452 0.89 SYNJ2 (0.82) SYNJ2SOSTAPPRECQLKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8110599-B2 AMPelopsin unsaturated sodium salt preparation and applications thereof FAN FULIN (CN) 2012-02-07 US claimed
US-8110599-B2 AMPelopsin unsaturated sodium salt preparation and applications thereof FAN FULIN (CN) 2012-02-07 US disclosed
US-20090054518-A1 AMPelopsin Unsaturated Sodium Salt Preparation and Applications thereof FAN FULIN 2009-02-26 US disclosed
EP-2005955-A1 FORMULATION OF UNSATURATED SALT OF AMPELOPSIN AND ITS APPLICATION Fan, Fulin (CN) 2008-12-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054518-A1 AMPelopsin Unsaturated Sodium Salt Preparation and Applications thereof NHERF1, SCLY, GRK1 SYNJ2 1818/4885SOST 3203/4885APP 2598/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.