SCHEMBL15545684

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15545096	0.85	KDM4E (0.39)	KDM4EL3MBTL1ALDH1A1HPGDCYP1A2
	SCHEMBL17467171	0.81	L3MBTL1 (0.36)	KDM4EL3MBTL1ALDH1A1HPGDCYP1A2
	SCHEMBL17467122	0.80	BACE1 (0.37)	KDM4EL3MBTL1ALDH1A1HPGDKMT2A
	SCHEMBL17467148	0.79	KDM4E (0.35)	KDM4EL3MBTL1ALDH1A1HPGDCYP1A2
	SCHEMBL15270753	0.74	KDM4E (0.47)	KDM4EL3MBTL1ALDH1A1HPGDCYP1A2
	SCHEMBL17467147	0.73	PAX8 (0.37)	KDM4EL3MBTL1ALDH1A1KMT2ATSHR
	SCHEMBL18013560	0.70	ALDH1A1 (0.41)	KDM4EL3MBTL1ALDH1A1HPGDCYP1A2
	SCHEMBL15545153	0.70	KDM4E (0.44)	KDM4EL3MBTL1ALDH1A1HPGDCYP1A2
	SCHEMBL29503711	0.69	NPSR1 (0.47)	KDM4EL3MBTL1ALDH1A1KMT2ACYP3A4
	SCHEMBL3464422	0.69	NPSR1 (0.47)	KDM4EL3MBTL1ALDH1A1KMT2ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.