Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9617411 | 0.75 | LMNA (0.50) | ALDH1A1HSD17B10MEN1LMNAMAPT | |
| SCHEMBL15558588 | 0.74 | CA1 (0.40) | ALDH1A1HSD17B10MEN1LMNAMAPT | |
| SCHEMBL813542 | 0.73 | MAOA (0.46) | ALDH1A1HSD17B10MEN1LMNAMAPT | |
| SCHEMBL813544 | 0.73 | MAOA (0.46) | ALDH1A1HSD17B10MEN1LMNAMAPT | |
| SCHEMBL29422894 | 0.72 | ALDH1A1 (0.35) | ALDH1A1HSD17B10MEN1LMNAMAPT | |
| SCHEMBL7214854 | 0.72 | ALDH1A1 (0.38) | ALDH1A1HSD17B10MEN1LMNAMAPT | |
| SCHEMBL15558221 | 0.71 | SETD7 (0.35) | ALDH1A1HSD17B10MEN1LMNAMAPT | |
| SCHEMBL15548375 | 0.71 | PTPN1 (0.33) | ALDH1A1HSD17B10MEN1LMNAMAPT | |
| SCHEMBL15548371 | 0.71 | PTPN1 (0.33) | ALDH1A1HSD17B10MEN1LMNAMAPT | |
| SCHEMBL979267 | 0.71 | CES1 (0.40) | ALDH1A1HSD17B10MEN1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210284621-A1 | CANNABINOIDS AND USES THEREOF | CORBUS PHARMACEUTICALS, INC. | 2021-09-16 | — | — | US | disclosed |
| EP-3801505-A1 | CANNABINOIDS AND USES THEREOF | Corbus Pharmaceuticals, Inc. (US) | 2021-04-14 | — | — | EP | disclosed |
| US-20170240521-A1 | PERIPHERALLY-ACTING CANNABINOID RECEPTOR AGONISTS FOR CHRONIC PAIN | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-08-24 | — | — | US | disclosed |
| US-9656981-B2 | Peripherally-acting cannabinoid receptor agonists for chronic pain | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-05-23 | — | — | US | disclosed |
| US-20150239859-A1 | PERIPHERALLY-ACTING CANNABINOID RECEPTOR AGONISTS FOR CHRONIC PAIN | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2015-08-27 | — | — | US | disclosed |
| WO-2014015298-A1 | PERIPHERALLY-ACTING CANNABINOID RECEPTOR AGONISTS FOR CHRONIC PAIN | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-01-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210284621-A1 | CANNABINOIDS AND USES THEREOF | CNR2, CNR1, FAAH | ALDH1A1 2486/4885HSD17B10 2000/4885MEN1 2697/4885 |
| US-20150239859-A1 | PERIPHERALLY-ACTING CANNABINOID RECEPTOR AGONISTS FOR CHRONIC PAIN | CNR2, CNR1, OPRL1 | ALDH1A1 3666/4885HSD17B10 3930/4885MEN1 4854/4885 |
| US-20170240521-A1 | PERIPHERALLY-ACTING CANNABINOID RECEPTOR AGONISTS FOR CHRONIC PAIN | CNR2, CNR1, OPRL1 | ALDH1A1 3666/4885HSD17B10 3930/4885MEN1 4854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.