SCHEMBL1556477

SCHEMBL1556477

CCCCC(C)C(N)CCCC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.48
SPHK1 Q9NYA1 2/20 0.39
ALDH1A1 P00352 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
DPP8 Q6V1X1 3/20 0.38
DPP7 Q9UHL4 3/20 0.38
TP53 P04637 2/20 0.38
DNM1 Q05193 2/20 0.38
SLC15A1 P46059 1/20 0.38
CYP2D6 P10635 2/20 0.37
GMNN O75496 1/20 0.37
LMNA P02545 1/20 0.37
POLB P06746 1/20 0.37
THPO P40225 1/20 0.37
MTOR P42345 1/20 0.37
BLM P54132 1/20 0.37
KDM4E B2RXH2 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4953066 0.93 OPRM1 (0.54) OPRM1SPHK1TP53DNM1CYP2D6
SCHEMBL4953074 0.93 OPRM1 (0.54) OPRM1SPHK1TP53DNM1CYP2D6
SCHEMBL19577535 0.93 OPRM1 (0.54) OPRM1SPHK1TP53DNM1CYP2D6
SCHEMBL4953708 0.93 OPRM1 (0.54) OPRM1SPHK1TP53DNM1CYP2D6
SCHEMBL22193776 0.92 OPRM1 (0.46) OPRM1SPHK1ALDH1A1TDP1DPP8
SCHEMBL7088385 0.92 OPRM1 (0.59) OPRM1SPHK1TP53CYP2D6GMNN
SCHEMBL7288247 0.92 OPRM1 (0.46) OPRM1SPHK1ALDH1A1TDP1DPP8
SCHEMBL11035498 0.91 DPP8 (0.41) OPRM1SPHK1ALDH1A1TDP1DPP8
SCHEMBL30989582 0.90 OPRM1 (0.56) OPRM1SPHK1TP53CYP2D6GMNN
SCHEMBL28515707 0.90 OPRM1 (0.56) OPRM1SPHK1TP53CYP2D6GMNN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109563630-B Surface-treated metal sheet and method for producing surface-treated metal sheet 株式会社神户制钢所 2021-10-08 CN disclosed
CN-108699704-B Surface-treated zinc-based steel sheet having excellent appearance 株式会社神户制钢所 2021-02-05 CN disclosed
CN-109563630-A Surface-treated metal sheet and method for producing surface-treated metal sheet 株式会社神户制钢所 2019-04-02 CN disclosed
CN-108699704-A The surface treated zinc-based metal plated steel sheet of good appearance 株式会社神户制钢所 2018-10-23 CN disclosed
CN-103121316-B The surface-treated metal plate of corrosion resistance and excellent electric conductivity KOBE STEEL LTD. (JP) 2015-09-16 CN disclosed
WO-2011049660-A1 PROCESS FOR PREPARING A 1,2-ETHYLENEDIAMINE OR 1,2-PROPYLENEDIAMINE DOW GLOBAL TECHNOLOGIES INC. (US) 2011-04-28 WO disclosed
US-20110092741-A1 PROCESS FOR PREPARING A 1,2-ETHYLENEDIAMINE OR 1,2-PROPYLENEDIAMINE FAZIO MICHAEL J 2011-04-21 US disclosed
CN-100507075-C Surface-treated galvanized steel sheet, method for producing same, and surface-treating agent KOBE STEEL LTD (JP) 2009-07-01 CN disclosed
CN-1806065-A Surface-treated, zinc-plated steel sheet having excellent resistance to tape peeling, method for producing same, and surface treatment agent KOBE STEEL LTD (JP) 2006-07-19 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110092741-A1 PROCESS FOR PREPARING A 1,2-ETHYLENEDIAMINE OR 1,2-PROPYLENEDIAMINE ADH1A, ADH1C, ADH5 OPRM1 641/4885SPHK1 2134/4885ALDH1A1 109/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.