Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT4 | P35916 | 20/20 | 0.45 |
| ▸ | KDR | P35968 | 7/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15502390 | 0.83 | FLT4 (0.64) | FLT4KDR | |
| SCHEMBL9838551 | 0.74 | ALDH1A1 (0.48) | — | |
| SCHEMBL5249724 | 0.66 | ALDH1A1 (0.38) | — | |
| SCHEMBL28107473 | 0.66 | ACVRL1 (0.44) | FLT4KDR | |
| SCHEMBL30183586 | 0.66 | HTR1A (0.44) | — | |
| SCHEMBL6547529 | 0.66 | HTR1A (0.44) | — | |
| SCHEMBL7104060 | 0.65 | TDP1 (0.37) | — | |
| SCHEMBL29038093 | 0.65 | JUN (0.39) | — | |
| SCHEMBL2693816 | 0.65 | ALDH1A1 (0.43) | — | |
| SCHEMBL30519922 | 0.65 | JUN (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2885291-A1 | VEGFR3 INHIBITORS | Cancer Therapeutics Crc Pty Limited (AU) | 2015-06-24 | — | — | EP | disclosed |
| WO-2014026243-A1 | VEGFR3 INHIBITORS | CANCER THERAPEUTICS CRC PTY LIMITED (AU) | 2014-02-20 | — | — | WO | disclosed |