Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.72 |
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.60 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | TNF | P01375 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | PDE6D | O43924 | 1/20 | 0.55 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.55 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL229324 | 0.89 | MEN1 (0.78) | MEN1KMT2ALMNAALDH1A1AGTR1 | |
| SCHEMBL9740603 | 0.87 | ALDH1A1 (0.66) | MEN1KMT2ALMNAALDH1A1AGTR1 | |
| SCHEMBL28487275 | 0.85 | AGTR1 (0.76) | MEN1KMT2ALMNAALDH1A1AGTR1 | |
| SCHEMBL29411886 | 0.85 | AGTR1 (0.76) | MEN1KMT2ALMNAALDH1A1AGTR1 | |
| SCHEMBL4952279 | 0.84 | AGTR1 (0.78) | MEN1KMT2ALMNAALDH1A1AGTR1 | |
| SCHEMBL103530 | 0.84 | MEN1 (1.00) | MEN1KMT2ALMNAALDH1A1CYP1A2 | |
| SCHEMBL7545509 | 0.83 | AGTR1 (0.76) | MEN1KMT2ALMNAALDH1A1AGTR1 | |
| SCHEMBL9518580 | 0.83 | MEN1 (0.61) | MEN1KMT2ALMNAALDH1A1AGTR1 | |
| SCHEMBL7545514 | 0.83 | AGTR1 (0.76) | MEN1KMT2ALMNAALDH1A1AGTR1 | |
| SCHEMBL9764119 | 0.83 | AGTR1 (0.76) | MEN1KMT2ALMNAALDH1A1AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014027053-A1 | BENZIMIDAZOLES FOR THE TREATMENT OF CANCER | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2014-02-20 | — | — | WO | disclosed |