SCHEMBL15569856

SCHEMBL15569856

N[SH](=O)=O.O=[N+]([O-])c1c[nH]cn1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.33
NAMPT P43490 1/20 0.33
XDH P47989 1/20 0.33
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL44903 0.90
SCHEMBL27932470 0.88
SCHEMBL28216165 0.72 ALDH1A1 (0.33) RAB9A
Ethoxycarbonyl Group SCHEMBL27927717 0.72 LMNA (0.33)
SCHEMBL28292215 0.71 MITF (0.37) RAB9A
SCHEMBL28216523 0.70 MAPT (0.33) RAB9A
Ethyl Propionate SCHEMBL28290764 0.70 MITF (0.48) CYP3A4RAB9A
SCHEMBL29708599 0.69
SCHEMBL31095437 0.63 HTR2A (0.41) RAB9A
SCHEMBL6972639 0.61 FBP1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014030142-A2 NITROIMIDAZOLE COMPOUNDS AND THEIR USE IN CANCER THERAPY AUCKLAND UNISERVICES LIMITED (NZ) 2014-02-27 WO disclosed