Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.60 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TAS2R31 | P59538 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6565166 | 0.85 | RIPK1 (0.78) | RIPK1ABCG2MEN1KMT2ARAB9A | |
| SCHEMBL27442244 | 0.84 | RIPK1 (0.59) | RIPK1ABCG2MEN1KMT2ARAB9A | |
| SCHEMBL30593801 | 0.78 | ALDH1A1 (0.65) | RIPK1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL20094733 | 0.75 | RIPK1 (1.00) | RIPK1ABCG2MEN1KMT2ARAB9A | |
| Pinostrobin SCHEMBL30238575 | 0.74 | ABCG2 (1.00) | ABCG2MEN1KMT2ARAB9ANPC1 | |
| Pinostrobin SCHEMBL1485747 | 0.74 | ABCG2 (1.00) | ABCG2MEN1KMT2ARAB9ANPC1 | |
| Pinostrobin SCHEMBL7648566 | 0.74 | ABCG2 (1.00) | ABCG2MEN1KMT2ARAB9ANPC1 | |
| Pinostrobin SCHEMBL31264673 | 0.74 | ABCG2 (1.00) | ABCG2MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL27766387 | 0.73 | LDHA (0.39) | RIPK1ABCG2MEN1KMT2ARAB9A | |
| SCHEMBL9444373 | 0.73 | MEN1 (0.49) | RIPK1ABCG2MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2888012-B1 | ORAL CARE | UNIV PRETORIA (ZA) | 2020-06-17 | — | — | EP | disclosed |
| EP-2888012-A2 | ORAL CARE | University of Pretoria (ZA) | 2015-07-01 | — | — | EP | disclosed |
| US-20150174059-A1 | ORAL CARE | UNIVERSITY OF PRETORIA (ZA) | 2015-06-25 | — | — | US | disclosed |
| WO-2014033625-A2 | ORAL CARE | UNIVERSITY OF PRETORIA (ZA) | 2014-03-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150174059-A1 | ORAL CARE | NOP2, POLR1C, DPM1 | RIPK1 4306/4885ABCG2 4716/4885MEN1 4410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.