Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10192324 | 0.84 | MMP1 (0.32) | RXRARXRBALOX5PTGS2 | |
| SCHEMBL11840980 | 0.80 | PTGS2 (0.39) | PTGS2 | |
| SCHEMBL11840724 | 0.79 | PTGS2 (0.38) | PTGS2 | |
| SCHEMBL8679236 | 0.75 | RXRA (0.42) | RXRARXRBRXRGALOX5PTGS2 | |
| SCHEMBL30500509 | 0.75 | RXRA (0.42) | RXRARXRBRXRGALOX5PTGS2 | |
| SCHEMBL13712973 | 0.75 | GABRA1 (0.43) | — | |
| SCHEMBL24869049 | 0.73 | RECQL (0.33) | — | |
| SCHEMBL10598465 | 0.72 | MEN1 (0.47) | RXRARXRBRXRG | |
| SCHEMBL19078687 | 0.71 | ESR2 (0.52) | RXRARXRBRXRGPTGS2 | |
| SCHEMBL18085911 | 0.71 | MAPT (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8674095-B2 | Compounds for treating neuropsychiatric conditions | AFRAXIS HOLDINGS, INC. (US) | 2014-03-18 | — | — | US | disclosed |