Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.66 |
| ▸ | NPC1 | O15118 | 6/20 | 0.66 |
| ▸ | F2R | P25116 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | PNLIP | P16233 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13192837 | 0.87 | NPC1 (0.70) | RAB9ANPC1F2RHPGDMAPT | |
| SCHEMBL15472302 | 0.84 | NPC1 (0.66) | RAB9ANPC1F2RHPGDMAPT | |
| SCHEMBL24934209 | 0.82 | F2R (0.67) | RAB9ANPC1F2RMAPTLMNA | |
| SCHEMBL12059130 | 0.82 | NR1H4 (0.64) | RAB9ANPC1HPGDMAPTLMNA | |
| SCHEMBL18330527 | 0.78 | TDP1 (0.80) | RAB9ANPC1HPGDMAPTLMNA | |
| SCHEMBL11646418 | 0.77 | MITF (0.56) | RAB9ANPC1HPGDMAPTLMNA | |
| SCHEMBL12190104 | 0.77 | KDM4E (0.58) | RAB9ANPC1HPGDMAPTLMNA | |
| SCHEMBL25918283 | 0.75 | MEN1 (0.66) | RAB9ANPC1MAPTLMNAGAA | |
| SCHEMBL1810666 | 0.75 | RAB9A (0.71) | RAB9ANPC1F2RHPGDMAPT | |
| SCHEMBL11646313 | 0.75 | MAPT (0.53) | RAB9ANPC1HPGDMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9624239-B2 | Protein kinase inhibitors | PHARMASCIENCE INC. (CA) | 2017-04-18 | — | — | US | disclosed |
| WO-2012135944-A9 | PROTEIN KINASE INHIBITORS | PHARMASCIENCE INC. (CA) | 2014-01-09 | — | — | WO | disclosed |